CANCER BIOLOGY

University of East Anglia

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DNA DAMAGE AND REPAIR
  • DNA DAMAGE AND REPAIR

  • Lecture notes • 6 pages • 2024
  • * DNA Repair & Cancer * Cancer & Genomic Instability * Sources of DNA Damage * Types of DNA Damage * DNA Repair Pathways * Defects on DNA Repair & Links with Human Disease * MMR & HNPCC * DNA Damage & Apoptosis * P53 * Cancer Therapy and DNA Damage * BRCA1 & BRCA2 and PARP * POLY-ADP-RIBOSE POLYMERASE (PARPs)
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Chemotherapy and Drug Resistance
  • Chemotherapy and Drug Resistance

  • Lecture notes • 6 pages • 2024
  • *Conventional Cancer Treatment * Therapeutic Window *Conventional Therapies * Gleevec *Resistance *Phenomenon *P-Glycoprotein * Drug Metabolism *Glutathione S Transferase *Dihydrofolate Reductase (DHFR)
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