CANCER BIOLOGY
University of East Anglia
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DNA DAMAGE AND REPAIR
- Lecture notes • 6 pages • 2024
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* DNA Repair & Cancer 
* Cancer & Genomic Instability 
* Sources of DNA Damage 
* Types of DNA Damage 
* DNA Repair Pathways 
* Defects on DNA Repair & Links with Human Disease 
* MMR & HNPCC 
* DNA Damage & Apoptosis 
* P53 
* Cancer Therapy and DNA Damage 
* BRCA1 & BRCA2 and PARP 
* POLY-ADP-RIBOSE POLYMERASE (PARPs)
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Chemotherapy and Drug Resistance
- Lecture notes • 6 pages • 2024
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- £7.16
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*Conventional Cancer Treatment 
* Therapeutic Window 
*Conventional Therapies 
* Gleevec 
*Resistance 
*Phenomenon 
*P-Glycoprotein 
* Drug Metabolism 
*Glutathione S Transferase 
*Dihydrofolate Reductase (DHFR)
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