Drug discovery - Study guides, Revision notes & Summaries

Pharmacology /INTRODUCTION TO DRUG DISCOVERY TEST 100% VERIFIED SOLUTIONS 2023/2024 Who used Quinine and what for? • South American Indians: treat chills and fever • Europeans: Treat fever and malaria What is quinine used for? treat malaria What was opium poppy initially used for? Analgesic effects What drugs are found in opium poppy • Morphine (analgesic agent) • Codeine (cough suppressant) Erythroxylum coca contains coca Erythroxylum coca is used for • Stimul...

What is the Chemical Manufacturing and Control group (CMC) - ANSWER-The group that typically deals with how and where the compound will be prepared. Their first task is to optimize the synthesis of the drug, with an eye toward performing the reaction on very large scale...many reactions that we take for granted in a normal organic chemistry lab are not amenable to "very large scale" In large scale synthesis, it is best to avoid: - ANSWER-Reactions that need very low temperatures Slow, cont...

FL CDR Sample questions module 9-15 already passed A quarantine area at Prescription drug wholesale distributor is used to store: A) Expired drugs B) Damaged drugs C) Misbranded drugs D) Adulterated drugs E) All of the above* Upon receipt of a prescription drug, prior to accepting the permittees inventory, a prescription drug wholesale distributor must perform which of the following tasks? A) Visually examine each outside shipping container for identity and to prevent accepting contaminated...

Drug Discovery Final Exam | with complete solution | Latest 2024/25

Lipinski's Rule of 5 - ANSWER-A successful drug meets these criteria: -LogP<5 -molecular weight <500 g/mol - hydrogen bond donors <5 -hydrogen bond acceptors <10 -rotatable bonds<10 logD - ANSWER-distribution between all forms of drug (logD<5) Polar surface area - ANSWER-the surface area of nitrogen's, oxygens, and their attached protons on a molecule What is the problem with Lipinski's rules - ANSWER-the majority of drugs that are being focused on only adhere ...

Innate immune system - ANSWER-nonspecific defense mechanisms that come into play immediately or within hours of an antigen's appearance in the body -antigens are foreign substances such as toxins, bacteria, viruses -the defense mechanisms involve physical barriers such as skin, chemicals in blood, and immune system cells that attack foreign cells in body the chemical or molecular properties of the antigen - ANSWER-what is the innate immune response activated by? acquired immune system -...

Pharmacology 1 Exam 1- PA First Semester Pharmacology Drug Development Process Phases Drug Discovery Pre-Clinical Clinical Trials (phases 1, 2, 3) FDA Review Production What happens between Clinical Trials and FDA Review? NDA is sent to the FDA How much does it cost to produce a new drug? $1-2 billion dollars When does the

OPENSTAX MICROBIOLOGY TEST BANK OpenStax Microbiology THIS TEST BANK COVERS ALL CHAPTERS 1-26 OF THE BOOK 1 An Invisible World 1.1 What Our Ancestors Knew 1.2 A Systematic Approach 1.3 Types of Microorganisms 2 How We See the Invisible World 2.1 The Properties of Light 2.2 Peering Into the Invisible World 2.3 Instruments of Microscopy 2.4 Staining Microscopic Specimens 3 The Cell 3.1 Spontaneous Generation 3.2 Foundations of Modern Cell Theory 3.3 Unique Characteristics of Prokaryotic Cells 3.4 ...

OPENSTAX MICROBIOLOGY TEST BANK OpenStax Microbiology THIS TEST BANK COVERS ALL CHAPTERS 1-26 OF THE BOOK 1 An Invisible World 1.1 What Our Ancestors Knew 1.2 A Systematic Approach 1.3 Types of Microorganisms 2 How We See the Invisible World 2.1 The Properties of Light 2.2 Peering Into the Invisible World 2.3 Instruments of Microscopy 2.4 Staining Microscopic Specimens 3 The Cell 3.1 Spontaneous Generation 3.2 Foundations of Modern Cell Theory 3.3 Unique Characteristics of Prokaryotic Cells 3.4 ...

Pharmacology /INTRODUCTION TO DRUG DISCOVERY TEST 100% VERIFIED SOLUTIONS 2023/2024 Who used Quinine and what for? • South American Indians: treat chills and fever • Europeans: Treat fever and malaria What is quinine used for? treat malaria What was opium poppy initially used for? Analgesic effects What drugs are found in opium poppy • Morphine (analgesic agent) • Codeine (cough suppressant) Erythroxylum coca contains coca Erythroxylum coca is used for • Stimul...