Ciclosporin - Study guides, Revision notes & Summaries

NRNP 6566 Mid-term Study Guide Week 1 to 5 Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormone synthesis and br...

Medicine Nephrology MCQs/MRCP Final Exam Questions and Answers 2024 Graded A+. Question 1 of 82 A 24-year-old woman is diagnosed as having nephrotic syndrome after being investigated for proteinuria. A diagnosis of minimal change glomerulonephritis is ade. What is the most appropriate initial treatment to reduce proteinuria? A. Protein restriction in diet B. No treatment shown to effective C. Angiotensin-converting-enzyme inhibitor D. Diuretic E. Prednisolone -------------------------...

Medicine Nephrology MCQs/MRCP Final Exam Questions and Answers 2024 Graded A+. Question 1 of 82 A 24-year-old woman is diagnosed as having nephrotic syndrome after being investigated for proteinuria. A diagnosis of minimal change glomerulonephritis is ade. What is the most appropriate initial treatment to reduce proteinuria? A. Protein restriction in diet B. No treatment shown to effective C. Angiotensin-converting-enzyme inhibitor D. Diuretic E. Prednisolone -------------------------...

MRCP - Pharmacology Part 1 (Toxicity) Questions And Answers 100% Guaranteed Success. LFTs at baseline, 3 mo and 12 mo - correct answer. What monitoring do you need for statins? If AST goes up x3 from baseline and persists. Stop the statin and restart at a lower dose if symptoms resolve - correct answer. An AST rise of what level is enough to discontinue a statin? What do you do? - U&E at start, when increasing treatment or annually - Rise in creatinine up to 30%...

NRNP 6566 Midterm Study Guide 2024 with Complete Solutions. Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormon...

NRNP 6566 Midterm Study Guide 2024 with Complete Solutions. Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormon...

NRNP 6566 Midterm Study Guide 2024 with Complete Solutions. Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormon...

NRNP 6566 Midterm Exam Review Questions With Answers Latest (Graded A+) . Describe ways to lessen the hepatic first pass effect Some drugs, such as propranolol or enalapril, undergo significant metabolism during a single passage through the liver. This is called the first-pass effect. When drugs are highly susceptible to the first-pass effect, the oral dose needed to cause a response will be significantly higher than the intravenous dose used to cause the same response. Alternative routes of...

NRNP 6566 Midterm Exam Questions and Answers | Latest Study Guide Graded A+. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for h...

NRNP 6566 / NRNP6566 Midterm Exam Questions and Answers Latest Updated (Score A+). Describe the affect on low and high albumin levels on active drug levels especially for drugs that are highly protein bound. Albumin is the plasma protein with the greatest capacity for binding drugs. Binding to plasma proteins affects drug distribution into tissues, because only drug that is not bound is available to penetrate tissues, bind to receptors, and exert activity. As free drug leaves the bloodstrea...