Gpcr activation Study guides, Revision notes & Summaries

Why is celecoxib selective for COX-2 inhibition as compared to COX-1 inhibition? COX-1 contains Ile-523, whereas COX-2 contains Val-523, which permits celecoxib binding. COX-1 contains Ile-523, whereas COX-2 contains Val-523, which blocks celecoxib binding. COX-1 contains Val-523, whereas COX-2 contains Ile-523, which permits celecoxib binding. COX-1 contains Val-523, whereas COX-2 contains Ile-523, which blocks celecoxib binding. COX-2 is located in the endoplasmic reticulum where ...

Week 6 UNE Medical Biochemistry Review Exam Questions With 100% Correct Answers Glycogen is stored primarily in the: - answerliver and skeletal muscles Pathway for synthesis and degradation are identical. True or False - answerTrue Enzymes used for Glycogen synthesis - answerPhosphoglucomutase, UDPGlc pyrophosphorylase, and Glycogen synthase Glycogen synthesis - UDPGlc pyrophosphorylase: - answerGlucose 1-P + UTP → UDPGlc Glycogen synthesis - Phosphoglucomutase - answerGlucose 6-P is i...

Week 6 UNE Medical Biochemistry Review Exam Questions With 100% Correct Answers Glycogen is stored primarily in the: - answerliver and skeletal muscles Pathway for synthesis and degradation are identical. True or False - answerTrue Enzymes used for Glycogen synthesis - answerPhosphoglucomutase, UDPGlc pyrophosphorylase, and Glycogen synthase Glycogen synthesis - UDPGlc pyrophosphorylase: - answerGlucose 1-P + UTP → UDPGlc Glycogen synthesis - Phosphoglucomutase - answerGlucose 6-P is i...

As the Metabolic Syndrome progresses towards overt type 2 diabetes, symptoms typically arise chronologically. Which of the following arrangements best represents the chronological order of their development, from earliest to latest. A. Hyperinsulinemia, insulin resistance, central adiposity, retinopathy. B. Central adiposity, insulin resistance, hyperinsulinemia, retinopathy C. Retinopathy, central adiposity, insulin resistance, hyperinsulinemia D. Insulin resistance, hyperinsulinemia, cen...

Week 6 UNE Medical Biochemistry Review Exam Questions With 100% Correct Answers Glycogen is stored primarily in the: - answerliver and skeletal muscles Pathway for synthesis and degradation are identical. True or False - answerTrue Enzymes used for Glycogen synthesis - answerPhosphoglucomutase, UDPGlc pyrophosphorylase, and Glycogen synthase Glycogen synthesis - UDPGlc pyrophosphorylase: - answerGlucose 1-P + UTP → UDPGlc Glycogen synthesis - Phosphoglucomutase - answerGlucose 6-P is i...

The second messenger in the signaling cascade initiated by glucagon is: correct answer: cAMP Explanation: The second messenger for glucagon is cAMP. Review Module 2 GPCR signaling cascades When insulin is bound to its receptor an autophosphorylation event occurs and the IRS binds these phosphorylated sites through interactions with the: correct answer: SH2 domain Explanation: SH2 domains bind with phosphorylation sites and allow for docking of the IRS with the insulin receptor. Insulin...

An increase in ALL of the following would suggest trophic communication or support EXCEPT: 1.# of dendrites & synaptic terminals 2.Size of primary sensory cortex area receiving input from finger 3.Rate of respiration with exercise 4.Density of glial cells in memory areas - ️️3.Rate of respiration with exercise a "Do " communication: a relatively short term 'call to action' (activation) of the respiratory muscles to meet the immediate demands of exercise: increased need of oxygen and...

Receptors and Signaling, Protein Engineering Exam Questions With Verified Answers. What are the five characteristic features of signal transduction? - answer1. Specificity: a given stimulus triggers a specific response 2. Amplification: a small incoming signal causes a cascade that results in a large response 3. Modularity: different components can be mixed and matched to build a signaling pathway 4. Desensitization: the ability to turn a signaling pathway off 5. Integration: the ability...

What purpose does glycogen degradation and synthesis serve in animals? correct answers Liver glycogen is short-term energy which provides a way to store and release glucose in response to blood glucose levels. Which of the following is correct concerning the regulation of glycogen metabolism by hormones? -Glycogen phosphorylase is active when phosphorylated, which occurs in response to insulin. -Glucagon activates PKA, which inactivates glycogen synthase -Epi has the same effect as insul...

parasympathetic; vagus nerve; cardiac ganglion; acetylcholine; postganglionic; acetylcholine; GPCR; conductile; SA correct answers In the _____ branch of the autonomic nervous system, neurons in the brain stem extend processes into the periphery in _____ and form synapses in the _____ where they release the neurotransmitter _____ which binds to the input region of the _____ neuron. This neuron releases ______ that binds to _____ receptors on _____ cardiomyocytes in the _____ node, which nor...