Ipilimumab - Study guides, Revision notes & Summaries

ABSITE Study guide Exam Questions with Key Marking Scheme Updated 2024/2025 The best treatment option for a simple unilocular cystic mass in the mesentery of the small bowel - correct answer enucleation In post-op pts, what % of prescribed opioid pills were not taken - correct answer 72% Chemo drug that is a monoclonal Ab against PD-1 receptors on T cells used in melanoma, bladder cancer, RCC, NSCLC - correct answer Pembrolizumab Chemo drug that is a monoclonal Ab that blocks CTLA-4 ...

ESMO Exam Questions and Answers checkpoint inhibitors --> enhance immune system to kill the cancer cells - Answer-true anti-CTLA-4 drugs - Answer-ipilimumab (tremelimumab) anti-PD-1 drugs - Answer-Nivolumab Pembrolizumab (PDR001) anti-PD-L1 drugs - Answer-atezolimumab durvalumab avelumab tumors with what have better responses to and better survival after PD-(L)1 therapy? - Answer-tumors with IFN-gamma gene profile high level of infiltrative CD8+ T cells true / ...

Doxorubicin Cardiotoxic TISSUE VESICANT Baseline MUGA and total dose (CONCERN at 550 mg/m2) URINE=RED IF EXTRAVASATION OCCURS= cool/ice + Totect Idamycin Cardiotoxic (cardiomyopathy) Bleomycin AVOID oxygen supplementation Methotrexate Leukovorin decreases cytotoxicity Pemetrexed Vitamin B12 & folic acid supplements to decrease toxicity Fludarabine Immunosuppression Thioguanine Bone Marrow Suppression Stomatitis/Mucositis 5-FU *Stomati...

Predictors of PDL1/PD1 inhibitor response Presence of tumor CD8 cell infiltration High cancer genome burden High levels of cancer PD-L1 expression (PD1 is on the cytotoxic T cell) Ipilimumab CTLA4 inhibitor Nivolumab PD-1 inhibitor Regorafenib VEGF inhibitor Bevacizumab Monoclonal antibody against VEGF-A. Inhibits angiogenesis. Pembrolizumab PD-1 inhibitor Atezolizumab PD-L1 inhibitor Avelumab PD-L1 inhibitor Durvalumab PD-L1 inhibitor Cemiplimab PD-1 inhibitor fo...

Predictors of PDL1/PD1 inhibitor response Presence of tumor CD8 cell infiltration High cancer genome burden High levels of cancer PD-L1 expression (PD1 is on the cytotoxic T cell) Ipilimumab CTLA4 inhibitor Nivolumab PD-1 inhibitor Regorafenib VEGF inhibitor Bevacizumab Monoclonal antibody against VEGF-A. Inhibits angiogenesis. Pembrolizumab PD-1 inhibitor Atezolizumab PD-L1 inhibitor Avelumab PD-L1 inhibitor Durvalumab PD-L1 ...

Chemo Certification Renewal Exam The standard states that gowns must: A. be disposable B. not have any closures or seams that HDs can pass through C. be changed every shift if there are no specific manufacturer recommendations D. both a & b - D. both a & b Which of the following is a general recommendation regarding the administration of hazardous drugs? A. A NIOSH-approved respirator is required for all intravenous administration. B. Reuse of gowns is appropriate if the...

The standard states that gowns must: A. be disposable B. not have any closures or seams that HDs can pass through C. be changed every shift if there are no specific manufacturer recommendations D. both a & b - answer D. both a & b Which of the following is a general recommendation regarding the administration of hazardous drugs? A. A NIOSH-approved respirator is required for all intravenous administration. B. Reuse of gowns is appropriate if the gown remains hung up in the s...

Oxaliplatin - Answer- NEUROTOXICITY AVOID COLD (neuropathies exacerbated by cold exposure) Dilute with D5W* Cyclophosphamide - Answer- HEMMORRAGHIC CYSTITIS Blood in urine -> fluids (sometimes Mesna) Temazolamide - Answer- Headache (crosses into CNS)*** Interferons - Answer- ACUTE: Flu-like Syndrome CHRONIC: Depression- BLACK BOX WARNING Interleukin-2 - Answer- Flu-like Syndrome Capillary Leak Syndrome Cabazitaxel - Answer- No PVC bags or tubing! Docetaxel - Answer- No PVC bags or ...

The standard states that gowns must: A. be disposable B. not have any closures or seams that HDs can pass through C. be changed every shift if there are no specific manufacturer recommendations D. both a & b D. both a & b Which of the following is a general recommendation regarding the administration of hazardous drugs? A. A NIOSH-approved respirator is required for all intravenous administration. B. Reuse of gowns is appropriate if the gown remains hung up in the same ...

Chemotherapy Certification Exam Questions and answers, 100% Accurate. VERIFIED. Doxorubicin - Cardiotoxic TISSUE VESICANT Baseline MUGA and total dose (CONCERN at 550 mg/m2) URINE=RED IF EXTRAVASATION OCCURS= cool/ice + Totect Idamycin - Cardiotoxic (cardiomyopathy) Bleomycin - AVOID oxygen supplementation Methotrexate - *Leukovorin decreases cytotoxicity* Pemetrexed - Vitamin B12 & folic acid supplements to decrease toxicity Fludarabine - Immunosuppression Thioguanine - Bone Marr...