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Lecture notes Cell Biology And Genetics - Protein Translocation
Learning outcomes - 
- Describe the signal hypothesis 
- Compare and contrast co-translational and post-translational translocation 
- Propose a model for protein translocation based on the structures of the SecY complex 
- Describe the biosynthesis of integral membrane proteins
- Lecture notes
- • 9 pages •
Learning outcomes - 
- Describe the signal hypothesis 
- Compare and contrast co-translational and post-translational translocation 
- Propose a model for protein translocation based on the structures of the SecY complex 
- Describe the biosynthesis of integral membrane proteins
Lecture notes Cell Biology And Genetics on Nuclear transport
Learning Outcomes - 
- Distinguish between the roles of GEF, GAP and Ran in nuclear transport 
- Propose how structures of α and β importins inform how cargo is transported
- Lecture notes
- • 4 pages •
Learning Outcomes - 
- Distinguish between the roles of GEF, GAP and Ran in nuclear transport 
- Propose how structures of α and β importins inform how cargo is transported
Lecture notes Cell Biology And Genetics on Vesicular Transport
Learning outcomes: 
- Understand experiments that led to the hypothesis of trafficking 
- Compare and contrast vesicle budding via COPI, COPII, and clathrin coats 
- Explain a molecular mechanism for docking and fusion of transport vesicles
- Lecture notes
- • 9 pages •
Learning outcomes: 
- Understand experiments that led to the hypothesis of trafficking 
- Compare and contrast vesicle budding via COPI, COPII, and clathrin coats 
- Explain a molecular mechanism for docking and fusion of transport vesicles
Lecture notes Cell Biology And Genetics on Cytoskeleton
Learning outcomes: 
- Compare and contrast cytoskeletal components 
- Explain how filament polarity can be identified and the role it plays in transport
- Lecture notes
- • 8 pages •
Learning outcomes: 
- Compare and contrast cytoskeletal components 
- Explain how filament polarity can be identified and the role it plays in transport
Lecture notes Cell Biology And Genetics on Extracellular Matrix
- Compare and contrast different types of cell junctions 
- Explain how structures of integrin and cadherin inform a molecular mechanism for cell adhesion
- Lecture notes
- • 9 pages •
- Compare and contrast different types of cell junctions 
- Explain how structures of integrin and cadherin inform a molecular mechanism for cell adhesion
Lecture notes Cell Biology And Genetics on Cell Signalling
Learning outcomes: 
Describe the general principles of cell signalling (amplification, ligands/receptors, G-proteins/kinases, distance, resetting, etc.), with reference to specific examples such as Nuclear Receptors, GPCRs, and RTKs
- Lecture notes
- • 7 pages •
Learning outcomes: 
Describe the general principles of cell signalling (amplification, ligands/receptors, G-proteins/kinases, distance, resetting, etc.), with reference to specific examples such as Nuclear Receptors, GPCRs, and RTKs
Lecture notes on Cell biology and Genetics - Cell Cycle
Learning outcomes covered: 
- Understand that the Cell Cycle is a universal feature of dividing cells from yeast to sea urchin to frog oocytes and human cells 
- Recall the names and order of the phases of the eukaryotic cell cycle and describe what happens in each 
- Describe how the Cell Cycle is regulated by CDKs and cyclins, and what happens when it becomes deregulated (i.e. cancer)
- Lecture notes
- • 8 pages •
Learning outcomes covered: 
- Understand that the Cell Cycle is a universal feature of dividing cells from yeast to sea urchin to frog oocytes and human cells 
- Recall the names and order of the phases of the eukaryotic cell cycle and describe what happens in each 
- Describe how the Cell Cycle is regulated by CDKs and cyclins, and what happens when it becomes deregulated (i.e. cancer)