Totect Study guides, Class notes & Summaries

Totect Correct Answer Anecdote for Doxorubicin Warm Compress Correct Answer Plant alkaloids and etoposide Bleomycin Correct Answer bad for the lungs Leucovorin Correct Answer potentiates the effects of 5-FU and decreases the effect of MTX Calvert Formula Components Correct Answer Area under the curve (AUC) Carboplatin Creatinine Clearance Aromatase Inhibitors Correct Answer used for postmenopausal women- osteoporosis Vesicant Administration Correct Answer Prior to non-vesican...

Neoadjuvant therapy does not increase survival when compared to adjuvant therapy. It only changes the timing of treatment and can change surgical options if the tumor is shrunk enough. If this occurs, the patient may only require a lumpectomy plus radiation therapy instead of needing a mastectomy Main benefit of neoadjuvant chemotherapy (breast cancer patient) A comprehensive geriatric assessment (CGA) is a multidisciplinary evaluation to assess life expectancy and risk of morbidity and ...

T/F To be characterized as a profession, considerable specialized training must be required. CORRECT ANSWER-T Histology is the study of CORRECT ANSWER-tissue T/F The purpose of having a procedure for specimen receipt is to monitor the specimen and the accompanying paperwork. CORRECT ANSWER-T T/F Accessioning is giving a specimen a common number, one that is not unique to the patient. CORRECT ANSWER-f T/F The tasks performed by the histotechnologist require patience, mechanical abilit...

fixitive used for specimens CORRECT ANSWER-10% neutral buffered Formalin Marking Margins CORRECT ANSWER-- to identify resection margins, if tumour too close to these margins they know they have to go in and cut more out - Guide to embedding What is used to clean grossing station CORRECT ANSWER-phenolic disenfectant or gluteroldehyde how long is specimens stored for CORRECT ANSWER-1-3 months some legal cases kept indefinitly Why is fresh tissue not stored? CORRECT ANSWER-Would decom...

Block Holder (Chuck) Knife & knife carrier Paul, ratchet feed wheel & adjustment screws CORRECT ANSWER-3 essential parts of microtome Block holder CORRECT ANSWER-Holds the tissue in position Knife and knife carrier CORRECT ANSWER-For actual cutting of tissue sections Pawl, ratchet feed wheel & adjustment screws CORRECT ANSWER-Lines up the tissue block in proper position with knife, adjusting thickness of tissue for successive sections Xylol CORRECT ANSWER-Parts of microtome should ...

Processing includes (no fixation) CORRECT ANSWER dehydration, clearing, and infiltration. Dehydration CORRECT ANSWER the removal of water, a process necessary to prepare the tissue for embedding in a nonaqueous medium such as paraffin, celloidin, and some plastics. Excessive dehydration CORRECT ANSWER when bound water may be removed in a nonadditive reaction. This results in hard and brittle tissue that is difficult to section. Incomplete dehydration CORRECT ANSWER of tissues during pro...

Place in a separate container CORRECT ANSWER-Match each listed item with the appropriate disposal method: Used silver nitrate Simply pour down the sink CORRECT ANSWER-Match each listed item with the appropriate disposal method: 1% alcohol Dilute first, pour down the sink CORRECT ANSWER-Match each listed item with the appropriate disposal method: Concentrated HCL Place in a biohazard bag CORRECT ANSWER-Match each listed item with the appropriate disposal method: Blood-stained...

What thickness are paraffin sections routinely cut? CORRECT ANSWER-4-6 um Why should the temperature of the flotation bath be set specifically at 5-10 °C below the melting point of the paraffin wax? CORRECT ANSWER-water bath that is too hot may distort tissue morphology Warm enough to relieve compression Cool enough so the wax does not melt What thickness are paraffin sections cut for the Luxol Fast Blue procedure? CORRECT ANSWER-10 - 15 um Why are paraffin blocks put on ice pr...

What are the two common staining methods for nucleic acid in histology? CORRECT ANSWER-1. Feulgen Reaction 2. Methyl Green-Pyronin Method (DNA/RNA) Feulgen Reaction tests for what? CORRECT ANSWER-DNA What does the Schiff reagent bind to in the Feulgen Reaction? CORRECT ANSWER-Aldehyde group created by the hydrolysis of DNA Why can't we use the Bouin fixative on tissues being tested with Feulgen? CORRECT ANSWER-Bouin hydrolyzes tissues In Feulgen reactions, what happens when the hyd...

Histotechnology test 2What is the consequence to improper clearing? - correct answers "Moth eaten" due to water still being in the tissues- improper dehydration Sections will crumble and fall out of block Shrink the centre of the tissue Why would a tissue shrink? - correct answers Wax is too hot What causes microscopic chatter? - correct answers Over dehydration seen most prominately at the ends of tissues What is the melting point do most paraffins? - correct answers 55-58 degr...