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Clinical PMHNP Exam 1 study questions and answers
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Which theory of depression was developed based on observing that patients who were being treated for Hep C developed depressive symptoms? A. The monoamine theory B. The inflammation theory C. The HPA axis theory D. The stress-diathesis theory b. The inflammation theory Which of the foll...

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  • September 22, 2023
  • 25
  • 2023/2024
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Clinical PMHNP Exam 1 study questions
and answers
Which theory of depression was developed based on observing that patients who were being
treated for Hep C developed depressive symptoms?
A. The monoamine theory
B. The inflammation theory
C. The HPA axis theory
D. The stress-diathesis theory - answer b. The inflammation theory


Which of the following health conditions have a high co-morbidity with depression?
A. Hypertension
B. Asthma
C. Diabetes mellitus
D. Cardiovascular disease
E. Celiac disease
F. Cognitive impairment
G. Obesity
H. Cancer - answer A. Hypertension
C. Diabetes Mellitus
D. Cardiovascular disease
F. Cognitive impairment
G. Obesity
H. Cancer


In the Cutler video on depression, he highlights that there are 200 different ways to meet the
diagnostic criteria for depression.

,A. True
B. False - answer A. True


You have diagnosed a 53-year-old male with moderate MDD and he has declined psychotherapy
but has agreed to pharmacotherapy. He has diagnoses of Type 2 D.M. with a BMI of 32.1. Which
of the following antidepressants would provide a dual benefit for this patient?
A. Sertraline
B. Fluoxetine
C. Duloxetine
D. Mirtazapine - answer C. Duloxetine


Your patient was started on fluoxetine and after ten weeks of treatment his PhQ 9 score is 9.
What is your assessment of the efficacy of treatment based on this score?


A. The patient is in remission
B. The response is adequate but not in remission
C. The response is possibly inadequate
D. The response is inadequate - answer B. The response is adequate but not in remission


In the Star*D trial what percentage of patients treated for depression failed to respond to initial
pharmacotherapy?
A. 20%
B. 30%
C. 40%
D. 50% - answer D. 50%


In the Star D trial for patients that achieved remission what percentage relapsed after 4.4
months?
A. 25%

, B. 33%
C. 42%
D. 53% - answer B. 33%


When should adjunctive therapy be considered in treating MDD? (select all that apply)
A. Already tried 3 or > antidepressants
B. Initial antidepressant well tolerated
C. Partial response (>50% improvement)
D. Specific residual symptoms or side effects that can be targeted
E. Severity of depression, more functional impairment
F. Patient preference - answer B. Initial antidepressant well tolerated
D. Specific residual symptoms or side effects that can be targeted
E. Severity of depression, more functional impairment
F. Patient preference


Rates of remission increased with each additional change in therapy, especially when switching.
A. True
B. False - answer B. False


You have diagnosed your patient with Major Depressive Disorder and after six weeks of being
treated with fluoxetine 20 mg there is no treatment response. According to the VA/DoD
Guidelines for treatment of MDD what is the next step?
A. Switch to another monotherapy either an antidepressant or psychotherapy.
B. Switch to a different antidepressant
C. Augment with a second antidepressant
D. Augment with a second medication or psychotherapy
A. A, C
B. B

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