Lecture notes from Imperial College London, Biological Sciences BSc, 3rd year, Biodiversity Genomics (BG) module. These lecture notes provide an in-depth exploration of Quantitative Trait Locus (QTL) Mapping, a powerful tool in adaptation genomics for identifying the genetic basis of complex traits...
Friday 20 October 2023
Lecture 16 – Adaptation Genomics: Quantitative Trait Locus (QTL) Mapping
Genome scans and statistical tests can be used to identify regions of the genome that are
under selection
To understand what the genes are being selected for requires working from the genotype to
the phenotype (knocking out genes, how the gene affects development, how it functions in
the wild)
Instead starting with the phenotype – phenotypic variation in the population is heritable and
identify the genes responsible by QTL mapping using genetic markers
(Year 2 - Genetics)
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