Acetylcholinesterase Inhibitors
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Acetylcholinesterase Inhibitors (Lecture 7) Acetylcholine (ACh) Mechanism of Action 1. **How ACh Acts as a Neurotransmitter:** - **Synthesis:** ACh is synthesized from acetate and coenzyme A (CoA) in the presence of water. - **Storage:** ACh is stored in vesicles within the presynaptic neuron. - **Release:** ACh is released into the synaptic cleft upon presynaptic neuron stimulation. - **Receptor Activation:** ACh binds to either nicotinic or muscarinic receptors on the postsynaptic cell,...