CHEMISTRY 228
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1. Select the dominant form of the amino acid proline at pH 8. 
2. Solutions of the following optically active compounds are subjected to catalytic 
hydrochloric acid in water. After this treatment, some solutions do not display optical 
activity. Identify the compounds whose solutions retain opticalactivity. 
3. Which structure will react most rapidly with ethoxide, when ethoxide acts as a 
nucleophile? 
4. Of the labeled atoms, identify the most nucleophilic 
atom in the following structure: 
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