Anoikis - Study guides, Revision notes & Summaries
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GMS 6552 Exam 2 Questions and Answers 100% Correct!
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Oncogene - ANSWER-A gene that causes or contributes to the development of cancer 
 
Hallmarks of Cancer - ANSWER-Sustaining proliferative signaling 
Evading growth suppressors 
Activating invasion and metastasis 
Enabling replicative immortality 
Inducing angiogenesis 
Resisting cell death 
 
In vivo oncogenic evidence - ANSWER-Cause cancer when activated in a transgenic animal 
Render nontumorigenic cells tumorigenic 
Knock down or knock out in tumorigenic cells renders the cells nontumorigenic...
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GMS 6552 Exam 2 Questions and Answers 100% Correct!!
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Oncogene - ANSWER-A gene that causes or contributes to the development of cancer 
 
Hallmarks of Cancer - ANSWER-Sustaining proliferative signaling 
Evading growth suppressors 
Activating invasion and metastasis 
Enabling replicative immortality 
Inducing angiogenesis 
Resisting cell death 
 
In vivo oncogenic evidence - ANSWER-Cause cancer when activated in a transgenic animal 
Render nontumorigenic cells tumorigenic 
Knock down or knock out in tumorigenic cells renders the cells nontumorigenic...
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GMS6552 EXAM 2 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED
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GMS6552 EXAM 2 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED 
 
What is an Oncogene and what is it capable of doing? 
1. They can evade growth suppressors 
2. Drive cell proliferation 
3. Resist cell death (Apoptosis) 
4. Induce angiogenesis 
5. Enable replicative immortality 
6. Activate invasion and metastasis 
What are Proto-oncogenes 
Proto-Oncogene become oncogenes during carcinogeneisProto-Oncogene become oncogenes during carcinogeneis 
What is evidence of oncogene behaviors in V...
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GMS 6552 EXAM 2 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE
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GMS 6552 EXAM 2 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE 
 
MODULE 5 
An oncogene is defined as 
a gene that causes or contributes to the development of cancer 
What are the two types of evidence for oncogenic behavior? 
In vivo 
In vitro 
What are the 4 criteria for In vivo oncogenic behavior 
Cause cancer when activated in a transgenic animal 
Render nontumorigenic cells tumorigenic 
Knock down or knock out in tumorigenic cells renders the cells nontumorigenic 
Acti...
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GMS 6552 Exam 2 2024 with verified solutions
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Oncogene correct answersA gene that causes or contributes to the development of cancer 
 
Hallmarks of Cancer correct answersSustaining proliferative signaling 
Evading growth suppressors 
Activating invasion and metastasis 
Enabling replicative immortality 
Inducing angiogenesis 
Resisting cell death 
 
In vivo oncogenic evidence correct answersCause cancer when activated in a transgenic animal 
Render nontumorigenic cells tumorigenic 
Knock down or knock out in tumorigenic cells renders the ce...
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GMS 6552 Exam 1
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Agonist Activation of GPCR - answer-Ligand binds 
Promotes conformational changes 
Increase in R 
 
Inverse Agonist Inhibition of GPCR - answer-Ligand binds 
Stabilizes inactive receptor conformations 
 
Antagonist Inhibition of GPCR - answer-Do not effect basal constitutive signaling 
Do not affect receptor conformation when they bind 
 
GPCR Full Agonist - answer-Produces full biological response 
 
GPCR Partial Agonist - answer-Can only produce partial biological response even at saturating c...
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SI Practice Exam 4 |57 Questions with Verified Answers,100% CORRECT
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SI Practice Exam 4 |57 Questions with Verified Answers 
 
Which of the following statements is FALSE of the spliceosome and splicing mechanism? 
 
a. U1 snRNA base pairs with the 5' splice site 
b. The active spliceosome is produced when U1 and U3 snRNP exit 
c. U2 snRNA and U6 snRNA base pair to each other for the 1st reaction to occur 
d. U2 snRNA anneals to the branch site in the intron - CORRECT ANSWER b. The active spliceosome is produced when U1 and U3 snRNP exit 
 
Where are SR protein...
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N221 Pathophysiology Test 1 with complete solutions.
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codon - ANSWER-set of 3 bases on mRNA that codes for specific amino acid 
 
gene expression - ANSWER-degree to which a gene or group of genes is active 
 
chromosomes - ANSWER-small structures containing genetic info 
 
How many chromosomes/pairs? - ANSWER-46; 23 
 
the 22 pairs that are the same in males/females are called... - ANSWER-autologous 
 
Meoisis - ANSWER-when the chromosomes duplicate and cross over 
-produces 4 gametes with only 1 copy of each chromosome 
*cross over adds variety a...
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SI Practice Exam 4 |57 Questions with Verified Answers,100% CORRECT
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SI Practice Exam 4 |57 Questions with Verified Answers 
 
Which of the following statements is FALSE of the spliceosome and splicing mechanism? 
 
a. U1 snRNA base pairs with the 5' splice site 
b. The active spliceosome is produced when U1 and U3 snRNP exit 
c. U2 snRNA and U6 snRNA base pair to each other for the 1st reaction to occur 
d. U2 snRNA anneals to the branch site in the intron - CORRECT ANSWER b. The active spliceosome is produced when U1 and U3 snRNP exit 
 
Where are SR protein...
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Patho Exam 1 Norris, Tommie L. Lippincott CoursePoint for Norris Porth's Pathophysiology, 10th Test Bank
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Patho Exam 1 Norris, Tommie L. Lippincott CoursePoint for Norris: Porth's Pathophysiology, 10th Edition. Test Bank 
 
Atrophy - Ans: When confronted with a decrease in work demands or adverse environmental conditions, most cells are able to revert to a smaller size and a lower and more efficient level of functioning that is compatible with survival. 
 
What happens when cells atrophy? - Ans: Reduce their oxygen consumption and other cellular functions by decreasing the number and size of their ...
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