PIONEER ISBB questions well answered graded A+ 2023
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PIONEER ISBBCross-reactivity
A phenomenon that occurs when an antibody reacts with antigen that is structurally similar to the original antigen that induced antibody production
Karl Landsteiner
This person Immunized rabbits with haptens attached to a carrier molecule and then tested the se...
PIONEER ISBB
Cross-reactivity - correct answer A phenomenon that occurs when an antibody reacts with antigen that is
structurally similar to the original antigen that induced antibody production
Karl Landsteiner - correct answer This person Immunized rabbits with haptens attached to a carrier molecule and then tested the serum to measure how the antibodies produced reacted with different haptens
Ability of the individual to resist infection by means of normally present body functions - correct answer Characteristic of natural immunity
Alpha 1 antitrypsin - correct answer An acute phase reactant that acts to "mop up" or counteract the ‐
effects of neutrophil invasion during an inflammatory response
Dendritic cell - correct answer Considered the most effective APC in the body, as well as the most potent phagocytic cell
TLR2 - correct answer The Toll like receptor that recognizes teichoic acid and peptidoglycan: ‐
Chemotaxins - correct answer A substance released by bacteria, injured tissue, and white blood cells that
stimulates the movement of neutrophils and other white blood cells to the injured area
Natural killer cells - correct answer The primary cell of the natural immunity against intracellular organisms and tumor cells:
CD16 - correct answer Because of the presence of this CD, NK cells are able to make contact with and then lyse any cell coated with antibodies:
Passive - correct answer Identify the type of immunity: Infusion of serum or plasma containing high concentrations of antibody or lymphocytes from an actively immunized individual Spleen - correct answer Characterized as a large discriminating filter as it removes old and damaged cells and foreign antigens from the blood
CD 19, 20 and 21 - correct answer The CD marker of the B cells:
CD 2, 3, 4, 8 - correct answer CD marker of T cells
CD 2, 16, 56 - correct answer CD marker of NK cells
T cells - correct answer The role of this cell is to produce cytokines that contribute to immunity by stimulating B cells to produce antibodies, assisting in killing tumor cells or infected cells, and helping to regulate both the innate and adaptive immune response:
Type 2 - correct answer The type of T helper cells that help B cells produce antibodies against extracellular pathogens and to generally regulate B cell activity: ‐
IgM and IgD - correct answer The immunoglobulins present in the surface of a mature B cell:
Sheep RBC - correct answer The red cell used to differentiate the T cells from the B cells:
CD 19, CD 21, and MHC Class II - correct answer Markers present in the surface of the B Cells:
Ficoll-Hypaque - correct answer The reagent that will separate the lymphocytes such as the B cells and T cells from the other blood cells:
Immunogen - correct answer Macromolecules capable of triggering an adaptive immune response by inducing the formation of antibodies or sensitized T Cells in an immunocompetent Host
Alloantigen - correct answer Classify the type of antigen: The Fetus inside the womb of a woman Adjuvants - correct answer Substance administered with an immunogen that increases the immune response to provide immunity to a particular disease:
Class I and Class II - correct answer Major Histocompatibility Complex associated with antigen recognition and presentation:
B cell - correct answer The cell/s that is/are used in Class 2 HLA Typing:
Allorecognition - correct answer The ability of an individual organism to distinguish its own tissues from those of another.
Heavy chain - correct answer Immunoglobulin classes are based on:
Providing immunity for the newborn - correct answer All the following are true for an IgM antibody, EXCEPT:
IgD - correct answer Major membrane immunoglobulin found on the surface of a high proportion of B lymphocytes.
IL-2 - correct answer Formerly known as the T cell growth factor, this interleukin that causes the activation and proliferation of both the B cells and T cells:
C3, C5 - correct answer Complement proteins that is utilized in the alternative pathway:
C1 inhibitor - correct answer This complement regulator dissociates C1r and C1s from C1q:
C9 - correct answer No known disease is associated with a deficiency of this complement protein:
Type I, II, III - correct answer This hypersensitivity reaction/s is/are antibody mediated: ‐
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