I passed this course with an 8.5
Also, check out the neurodegenerative diseases summary with all the study material on that part of the course.
This overview contains (psychiatric diseases):
-symptoms
-prevalence
- Heritability
- Brain area's
- Genes
- Environmental factors
- treatmen...
[Meer zien]
Laatste update van het document: 10 maanden geleden
ADHD Depression Schizophrenia An3social and criminal behaviour
-a disorder of brain - Depressed or irritable mood Posi3ve symptoms An3social personality disorder:
matura3on delay - Anhedoniaà less pleasure - Psychosis (delusions and - Apparent lack of remorse
- Significant weight loss hallucina3on) - Aggressive, oWen violent
- Ina7en3on - Insomnia or hypersomnia - Disorganized speech behaviour
- Hyperac3ve - Psychomotor agita3on or - Distor3ons/exaggera3ons in - Inability to tolerate boredom
- Impulsivity retarda3on language + communica3on - Lack of access to own feelings
BUT ALSO - Fa3gue or loss of energy - disorganized behaviour and emo3ons
- Spontaneous - Feeling of worthlessness or - agita3on - Severe disrup3on in moral
- Crea3ve execu3ve guilt Nega3ve symptoms behaviour
- Divergent mind - Diminished ability to think or - blunted affect
- Vital concentrate - dysfunc3on of mo3va3on Subtypes
- High energy - Recurrent thoughts of death or - Anhedonia Psychopathy
- Fast thinking suicide - A-sociality - Callousness, manipula3veness,
Cogni3ve symptoms superficial charm
- A7en3onal problems - OWen highly intelligent
- Execu3ve dysfunc3on (PFC) - Grandiose sense of self-worth
(megalomania)
- Have ability but a reduced
Delusion= misinterpreta3on propensity for empathy
Hallucina3on= too much sensory input Conduct disorder: children ASPD
Prevalence 2-5% children age 6-16 10-20% will experience depression in 1% of populaAon More prevalent in male sex
their life (testosterone)
80% boys Onset in adolescence (15-25)
Twice as much females - Due to no LTP as NMDA-R
Symptoms persist into hypofuncAon
adulthood in 30-50% of Netherlands: 5%=800.000 adults and - More synapse pruning (starAng
cases 160.000 chronic in adolescence)
Co-morbidity with addicAon Co-morbidity with anxiety, ADHD, Concordance rate dizygoAc twins 17%
addicAon and other psychiatric diseases Concordance rate monozygoAc twins:
48%
Heritability ADHD: 75% Less severe depression: 25% Schizophrenia: 80% ASPD: 40-50%
AuAsm: 80% Major/chronic depression: 40-50% Personality: 50%
Bipolar:80%
, Brain area’s ¯PFC ¯PFC (BUT no performance deficit) ¯NMDA-receptor Decrease in moral judgement tasks
¯Cerebellum Amygdala ¯corAco-brainstem projecAon - PFC
¯Caudate nucleus (possibly normally: PFC inhibits (glutamate) - Amygdala
¯Corpus callosum amygdala) - Less tonic excitaAon of - cingulate
¯Amygdala ¯Hippocampus mesocorAcal pathway - Angular gyrus
¯Accumbens - Tail and headà risk - Less GABA release from Increase rule breaking behaviour
¯Hippocampus - Bodyà current state interneuron and thus Less tonic - PFC
¯Basal ganglia HPA axis inhibiAon of the mesolimbic - Amygdala
- Subtype: insomnia, loss of pathway - Angular gyrus
appeAte, weight loss and. Loss Mesolimbic dopamine These areas are probably ¯
of libido - Too much dopamine in ventral
- Increased corAsol and CRH striatum ¯PFC
- Reduced glucocorAcoid - PosiAve symptoms ¯Amygdala
receptors hippocampus and ¯MesocorAcal dopamine ¯Hippocampus
hypothalamus - Too liale dopamine in PFC Angular gyrus
¯BDNF - NegaAve and cogniAve Cingulate
- PFC and hippocampus symptoms Temporal cortex
Cytokines ¯GABA in thalamus
- Interleukin-6 and TNFa - Excess dopamine from the Failure of fear condiAoning
- Subtype: hypersomnia and meso-limbic pathway inhibits - Causal role for crime
weight gain GABA striatal-thalamic neuron - Amygdala dysfuncAon
DisrupAon chronobiological model - NMDA-R hypofuncAon causes
- early awake hypofuncAon of the corAco- Cavum septum pellucidum
Bacterial species striatal pathway and less - Marker for fetal limbic
- ¯Bacterial species that secrete acAvaAon of GABA striatal- maldevelopment
anA-inflammatory cytokines thalamic neuron - Significantly higher probability
- Bacterial species that secret - Less filtering> sensory overload of anA-social personality,
pro-inflammatory cytokines psychopathy, criminal charges
Default mode network and convicAons
- HyperconnecAvity
- More introspecAon and self-
referenAal thinking
Voordelen van het kopen van samenvattingen bij Stuvia op een rij:
Verzekerd van kwaliteit door reviews
Stuvia-klanten hebben meer dan 700.000 samenvattingen beoordeeld. Zo weet je zeker dat je de beste documenten koopt!
Snel en makkelijk kopen
Je betaalt supersnel en eenmalig met iDeal, creditcard of Stuvia-tegoed voor de samenvatting. Zonder lidmaatschap.
Focus op de essentie
Samenvattingen worden geschreven voor en door anderen. Daarom zijn de samenvattingen altijd betrouwbaar en actueel. Zo kom je snel tot de kern!
Veelgestelde vragen
Wat krijg ik als ik dit document koop?
Je krijgt een PDF, die direct beschikbaar is na je aankoop. Het gekochte document is altijd, overal en oneindig toegankelijk via je profiel.
Tevredenheidsgarantie: hoe werkt dat?
Onze tevredenheidsgarantie zorgt ervoor dat je altijd een studiedocument vindt dat goed bij je past. Je vult een formulier in en onze klantenservice regelt de rest.
Van wie koop ik deze samenvatting?
Stuvia is een marktplaats, je koop dit document dus niet van ons, maar van verkoper lvd26. Stuvia faciliteert de betaling aan de verkoper.
Zit ik meteen vast aan een abonnement?
Nee, je koopt alleen deze samenvatting voor €5,89. Je zit daarna nergens aan vast.
