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NR507 Final Exam Study Guide 2024 / NR 507 Week 8 Advanced Pathophysiology Questions and Answers (2024 / 2025) (Verified Answers)- Chamberlain

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FINAL EXAM - NR507 / NR 507 Advanced Pathophysiology
Newest Study Guide Questions and Verified Answers- Chamberlain



1. endometrial cycle

Ans>> The 28 days of the menstrual cycle as they apply to the

events in the uterus. The endometrial cycle has four subphases menstruation, the proliferativ

phase, and the secretory phase, and the ischemic phase .



2. proliferative phase

Ans>> The second phase of the uterine (endometrial) cycle, during which the endometrium

(shed off during menstration is rebuilt). This phase of the cycle is under the control of

estrogen, secreted from the follicle developing in the ovary during this time period. The

proliferative phase typically lasts from day 6 to day 14 of the menstrual cycle.



3. secretory phase

Ans>> The third phase of the uterin (endometrial) cycle, during which the rebuilt

endometrium is enhanced with glycogen and lipid stores. The secretory phase is primarily


,under the controll of progestone and estrogen (secreted from the copus luteum during this

time period), adn typically lasts from day 15 to day 28 of the menstrual cycle.




4. ischemic phase

Ans>> Approximately 3 days before menstruation to onset of men- struation. due to the

decreased production of estrogen or progesterone and the endometrium becomes blood

starved



5. menstrual cycle

Ans>> Cycle during which an egg develops and is released from an ovary and the uterus is

prepared to receive a fertilized egg.




6. Ovulation

Ans>> The process of releasing a mature ovum into the fallopian tube each month



7. uterine prolapse

Ans>> the condition in which the uterus slides from its normal position in the pelvic cavity

and sags into the vagina




,8. risk factors for uterine prolapse

Ans>> menopause, pregnancy, coughing, consti- pation, obesity, pelvic floor trauma,

vaginal birth, hysterectomy, connective tissue disorders, spina bifida




9. uterine prolapse treatment

Ans>> - kegel exercises

- estrogen therapy

- maintaining a healthy bmi, preventing constipation, treating chronic cough

- pessary

- surgical option s last resort



10. polycystic ovarian syndrome

Ans>> defined as two of the following three features

- irregular ovulation

-elevated adrogens (testosterone)

- and the appearance of polycystic ovaries on ultrasound



11. differentials for pcos


, Ans>> - thyroid dysfunction

- hyperprolactinemia

- congenital adrenal hyperplasia




12. Characteristics associated with PCOS

Ans>> -metabolic dysfunction

- dyslipidemia






,- insulin resistance

- obesity

13. polycystic ovarian syndrome treatment

Ans>> (1) diagnosis and education;

(2) lifestyle change - loss of 10% of body weight may help;

(3) birth control pills help with some symptoms;

(4) diabetes medications & dietary treatment may slowly normalize physiology (lower sugar,

lower insulin, fewer androgens)

14. testicular cancer

Ans>> malignant tumor in one or both testicles commonly develop- ing from the germ cells

that produce sperm; classified in two groups according to growth potential

15. conditions that increase risk of testicular cancer

Ans>> - being a man between the ages of 20-45

- cryptochidism (undescended testicle)

- family history

- previous testicle cancer

- white men are more likely

16. symptoms of breast cancer

Ans>> change in the shape or appearance of your breasts, skin or nipple changes such as



,dimpling of the skin, Squeeze each nipple gently to identify any discharge, chest pain (mets to

the lung)

17. signs of premenstrual dysphoric disorder

Ans>> physical - breast tenderness, abdominal bloating, headache and swelling of

extremities

emotional - depression anger, irritability and fatigue resolve with

menstruation

18. causes of dysfunctional uterine bleeding

Ans>> can be due to structural (polyp, malignancies and hyperplasia) or non structural

causes (coagulopathy, ovulatory dysfuction, endometrial

19. treatment for abnormal uterine bleeding

Ans>> - NSAIDS

(reduce prostaglandin, causes vasoconstriction, and decreased menstrual bleed- ing)

- Oral contraceptives

- Depo provera

- Levonorgestrel intrauterine device

20. Pathophysiology of prostate cancer

Ans>> - more than 90% of all cancer arising from the *prostate are adenocarcinomas

(glandular tissue)*



,- tumor becomes clinically relevant when local invasion or distant metastasis

-- starts with genetic mutation of luminal or basal cell

- RF are old age, obesity and high fat low fiber diet

21. Treatment of prostate cancer

Ans>> chemotherapy, radiation, hormones, prostatec- tomy






, 22. HPV and the development of cervical cancer

Ans>> HPV is a necessary precursor

to development of cervical dysplasia which is a necessary step for the cell changes leading to

cervical cancer

- multiple sex partners, smoking, long history of oral contraceptive use use of vaginal douches

and immunocompromised are at higher risk as well

23. body's process for adapting to high hormone levels

Ans>> negative feedback system occurs telling the endocrine system to stop secreting

hormones because there are enough hormones in the bloodstream

24. Cushing's syndrome

Ans>> - a condition caused by prolonged exposure to high levels of cortisol

- adrenal glands secrete cortisol

- severe muscle bone and skin breakdown

- elevated blood glucose levels and high insulin levels

- central obesity

- amplify catecholamines on blood vessels and causes high blood pressure

- inhibit gonadotropin releasing homone messing up ovarian and testicle function

- dampens inflammatory and immune response

- caused by medications (steroids)

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