inversely correlated correct answers two variables that move in opposite directions. If one increases the other decreases; and if one decreases the other increases.
A man with a CRC mutation that results in the synthesis of HSP110ΔE9 and a woman that does not carry this mutation in any of her t...
AAMC FL1 B/B || A Verified A+ Pass.
inversely correlated correct answers two variables that move in opposite directions. If one
increases the other decreases; and if one decreases the other increases.
A man with a CRC mutation that results in the synthesis of HSP110ΔE9 and a woman that does
not carry this mutation in any of her tissues have a child. What is the percent chance that the
child will inherit the CRC mutation?
A.0%
B.25%
C.50%
D.100% correct answers The answer to this question is A. According to the passage,
HSP110ΔE9 transcripts are not present in noncancerous tissue of people with MSI CRC. This
means that the deletion mutation in the HSP110 T17 microsatellite is a somatic, not germ line,
mutation. Therefore, the mutation will not be inherited, and the percent chance that the child of a
person with this mutation will inherit it is 0%.
if it was germ line, then it would be present in all tissues, not just cancerous ones.
The information in the passage best supports the conclusion that Intron 8 of HSP110 most likely
contains which of the following?
A.Stop codon
B.Splice acceptor site
C.HSP110 gene promoter
D.Partial coding sequence of HSP110 correct answers Deletions in the T17 microsatellite located
in Intron 8 of HSP110 cause Exon 9 to be omitted from the final mRNA sequence during pre-
mRNA processing. This would occur during alternative splicing, which strongly suggests that the
microsatellite contains sequences that influence splicing.
splice sites correct answers regions between the boundary of the introns and exons
branch point sequence correct answers - located 18-38 nucleotides upstream of 3' junction site
- it is a conserved sequence that always possesses an A nucleotide
-contains the adenosine residue which, as the intron is excised, will accept the guanosine residue
at the 5'-end of the intron.
clathrin protein correct answers Protein that maintains the vesicles for transportation in and out
of a cell
Clathrin-coated vesicles are found in all eukaryotic cells, but they are particularly enriched in the
brain, where they play a major role in the formation of neurotransmitter-containing pre-synaptic
vesicles required for synaptic nerve transmission.
, Pathogenic viruses and bacteria can gain entry into their target cell by making use of the host's
clathrin-dependent endocytic machinery, producing molecules on their surface that mimic
endogenous ligands to the host's cell receptors, thereby inducing the host's intracellular signalling
cascades.
chaperone correct answers facilitates proper protein folding and inhibits the formation of
nonfunctional protein aggregates.
cell adhesion molecules correct answers Cell adhesion molecules (CAMs) are proteins located on
the cell surface involved in binding with other cells or with the extracellular matrix (ECM) in the
process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other
and to their surroundings.
*transmembrane glycoproteins*
Ex) selectins, integrins, syndecans, and cadherins
*maintaining multicellular structure, signal transduction, pathogenesis of infectious organisms.
Chaperonins correct answers Chaperonins are a class of chaperones that assist in folding of
(largely) newly synthesized proteins with the help of ATP
does mrna have a promoters correct answers nope
transmembrane proteins correct answers enter the endomembrane system by docking at the
rough ER. This is facilitated by using a signal sequence. Nuclear localization signals are NOT
likely for a transmembrane protein
Pellagra also results from a deficiency of nicotinamide, which is synthesized from tryptophan.
Nicotinamide nucleotides are neither oxidized nor reduced during which step of cellular
respiration?
A.Glycolysis
B.Chemiosmosis
C.Citric acid cycle
D.Electron transport chain correct answers The answer is B because NAD+ is the oxidized form,
and NADH is the reduced form of nicotinamide adenine dinucleotide. NAD+ is neither reduced
to form NADH, nor is NADH oxidized to form NAD+ specifically during chemiosmosis.
Chemiosmosis correct answers A process for synthesizing ATP using the energy of an
electrochemical gradient and the ATP synthase enzyme.
the movement of ions across a semipermeable membrane, down their electrochemical gradient.
An example of this would be the generation of adenosine triphosphate (ATP) by the movement
of hydrogen ions (H+) across a membrane during cellular respiration or photosynthesis.
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