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MICR130 MODULE 9 EXAM QUESTIONS AND ANSWERS

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MICR130 MODULE 9 EXAM QUESTIONS AND ANSWERS What do hyaluronidase and kinase have in common? - Answer-They are both enzymes involved in evading host defense.. How are immune cells able to detect foreign pathogens? - Answer-They are able to detect structures on the surfaces of foreign cells tha...

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MICR130 MODULE 9 EXAM QUESTIONS
AND ANSWERS

What do hyaluronidase and kinase have in common? - Answer-They are both enzymes
involved in evading host defense..

How are immune cells able to detect foreign pathogens? - Answer-They are able to
detect structures on the surfaces of foreign cells that are not found in the host.

How does a capsule help certain bacteria evade detection by the immune system? -
Answer-The capsule is composed of polysaccharides that are similar to those found in
the host; thus, the immune system does not recognize it as foreign.

Which of the following microorganisms actually grows inside the macrophage? -
Answer-Tuberculosis bacterium

What are leukocidins? - Answer-Molecules that are capable of destroying phagocytes.

Measles viruses are capable of inactivating host defenses by? - Answer-suppressing
the immune system.

Meningitis and gonorrhea are caused by? - Answer-Neisseria species.

How do superantigens enable pathogens to hide from the immune system if they
actually stimulate the immune system? - Answer-They cause the immune system to
produce an exaggerated response, distracting it from the actual pathogen.

How can capsules enable bacteria to evade the immune system? - Answer-Capsules
block the complement biding sites on the surface of the pathogen.

Endotoxins are also known as? - Answer-Lipid A.

When would endotoxins be released from a bacterial cell? - Answer-When the cell dies

An exotoxin that has the ability to kill or damage host cells is referred to as a(n) -
Answer-cytotoxin.

A person who attended a picnic early in the day develops a very high fever and is
unresponsive by the evening. This person most likely has been exposed to a(n) -
Answer-superantigen.

, A patient who has been hospitalized with uncontrolled muscle spasms has probably
been infected with bacteria that secrete a(n) - Answer-neurotoxin.

In mice, the LD50 for staphylococcal enterotoxin is 1350 ng/kg, and the LD50 for Shiga
toxin is 250 ng/kg. Which of the following statements is true? - Answer-Shiga toxin is
more lethal than staphylococcal enterotoxin.

Which of the following would be an example of an infection initiated via the parenteral
route? - Answer-An individual contracts hepatitis B from an accidental stick with a
contaminated needle.

Which statement regarding endotoxins is true? - Answer-One consequence of
endotoxins is the activation of blood-clotting proteins.

Which type of bacterial enzyme helps spread Streptococcus pyogenes by digesting
blood clots? - Answer-fibrinolysin.

In which of the following cases would the Limulus amebocyte lysate (LAL) assay be
used? - Answer-to ensure that a sterilized medical device is free of endotoxin.

Which of the following statements about adherence is true? - Answer-Most bacterial
adhesins are glycoproteins or lipoproteins.

Which of the following toxins and does NOT match the description? - Answer-Vibrio
enterotoxin: a superantigen that destroys epithelial cells.

Which disease would be potentially propagated in an environment without functional
plumbing and in which drinking water is contaminated with sewage? - Answer-cholera.

Which of the following statements about lysogenic conversion is true? - Answer-
Exotoxin production by bacteria is frequently the result of a lysogenic infection.

Which of the following features of Salmonella prevent it from being phagocytosed? -
Answer-Flagella.

Where do Salmonella pathogens grow and replicate in the infected host? - Answer-
Inside phagocytes.


Given that the LD50 for staphylococcal enterotoxin is 1350 ng/kg and the LD50for Shiga
toxin is 250 ng/kg in mice, which of the following statements is true? - Answer-A much
larger dose of staphylococcal enterotoxin is needed to cause symptoms, compared to
that of Shiga toxin.

If an A-B toxin is missing its A component it cannot cause an intoxication because ____.
- Answer-the toxin does not have enzymatic activity.

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