MICR 270 EXAM QUESTIONS WITH ALL CORRECT ANSWERS – UPDATED!!
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MICR 270 EXAM QUESTIONS WITH ALL CORRECT ANSWERS – UPDATED!!
Pattern Recognition Receptor (PRR) - Answer-A receptor that recognises molecular patterns commonly shared by a number of pathogens; includes toll-like receptors.
Pathogen Associated Molecular Pattern (PAMP) - Answer-Associated with ...
MICR 270 EXAM QUESTIONS WITH
ALL CORRECT ANSWERS –
UPDATED!!
Pattern Recognition Receptor (PRR) - Answer-A receptor that recognises molecular
patterns commonly shared by a number of pathogens; includes toll-like receptors.
Pathogen Associated Molecular Pattern (PAMP) - Answer-Associated with groups of
pathogens → functional structures, repeated sequences of proteins, glycoproteins,
lipoproteins, amino acids, etc
Phagocytes - Answer-a type of cell within the body capable of engulfing and absorbing
bacteria and other small cells and particles.
Physical Barriers - Answer-skin and mucous membranes and chemicals they secrete
Plasmocytes - Answer-Arise from B-cells → secrete specialized antibodies that can bind
to free pathogens
Spleen - Answer-An organ that is part of the lymphatic system; it produces lymphocytes,
filters the blood, stores blood cells, and destroys old blood cells.
- Red pulp: Filters the blood
- White pulp: The site of development of immune responses against antigens in
bloodstream
T-cell - Answer-Cell-mediated immunity
Non phagocytic cells with specific receptors (T-cell receptors)
One T-cell expresses many TCR for same antigen, every T-cell recognizes different
antigen
CD4 = Helper
CD8 = Cytotoxic
Thymus - Answer-Site of T-cell development/maturation
Toll-Like Receptor (TLRs) - Answer-A type of pattern recognition receptor
, Vaccination - Answer-Injection of a weakened or mild form of a pathogen to adaptive
produce immunity
What are the goals of the immune system? - Answer-Discriminate: Recognize self from
non-self
Eliminate: Destroy non-self (pathogen) and altered self cells (cancer)
- Occurs through the ability of immune cells to initiate immune response
- Antigen enters → recognized → effector cells are activated → elimination
What are some of the dysfunctions experienced by the immune system? - Answer-
Autoimmunity and hypersensitivity
- Misdirected and Overly active immune system
Immunodeficiency
- Underactive immune system (e.g AIDs)
How are the lymphatic, circulatory, and immune systems related? - Answer-Lymphatic:
is the network that drains and filters lymph from blood and interstitial space
Circulatory: Where the lymph comes from/goes after filtration
Immune: Cells can travel between circulatory and lymphatic, can interact with antigen,
travel to site of infection, binds to antigen, and brings to the lymph nodes to eliminate
What are the primary lymphoid organs and their functions? - Answer-Thymus and Bone
Marrow
- T-cell and B-cell maturation to immunocompetent cells
What are the secondary lymphoid organs and their functions? - Answer-Spleen, lymph
nodes, MALT
Site of lymphocyte activation to activated effector cells
- Interaction with trapped antigens
What are hematopoietic stem cells? - Answer-Every blood cells arise from these cells
(e.g red blood cells, platelets, white blood cells).
What are the functions of erythrocytes/platelets? - Answer-Coagulation, wound healing,
fibrinolysis
What are the functions of mast cells? - Answer-To trigger acute inflammation
Act as a source of mediators, especially histamine
What are the 6 major infectious agents? - Answer-Bacteria
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