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BCH 369 EXAM 4 QUESTIONS WITH REVISED ANSWERS Which of the following does NOT correctly describe insulin's role in human metabolism? A) Insulin activates glycogenolysis. B) Insulin results in fatty acids being stored as fat in adipocytes. C) Insulin activates phosphatases. D) Insulin is relea...

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BCH 369 EXAM 4 QUESTIONS WITH
REVISED ANSWERS
Which of the following does NOT correctly describe insulin's role in human metabolism?
A) Insulin activates glycogenolysis.
B) Insulin results in fatty acids being stored as fat in adipocytes.
C) Insulin activates phosphatases.
D) Insulin is released in response to high blood glucose. - Answer-A) Insulin activates
glycogenolysis.

Given the following starting substrate, A, place the following reaction intermediates in
order of their appearance during a single cycle of β-oxidation.

A) D,C,B B) C,D,B C) B,C,D D) B,D,C E) D,B,C - Answer-E) D,B,C

Which of the following substances, if produced from the catabolism of an amino acid,
would be
glucogenic (in mammals)?1. Acetoacetate2. Pyruvate3. Acetyl-CoA4. Oxaloacetate
A) 1 only B) 4 only C) 1 and 2 D) 2 and 4 E) 1, 3 and 4 - Answer-D) 2 and 4

Skipping a meal would most likely cause a(n) ____________ in glycogen synthase
activity and a(n)
____________ in hormone-sensitive lipase activity.
A) decrease, decrease B) decrease, increase C) increase, decrease D) increase,
increase - Answer-B) decrease, increase

The process of converting NH4+ to NO2- and then NO3- is called
A) nitrogen fixation
D) denitrification
B) nitrogen reduction
E) nitrate oxidation
C) nitrification - Answer-C) nitrification

In adipocytes, why does the synthesis of triacylglycerols require an external supply of
glucose?
A) The synthesis of triacylglycerols requires glycerol 3-phosphate, which is derived from
glucose.
B) The synthesis of triacylglycerols requires glycerol, which is derived from glucose.
C) Glucose is required for the production of acetyl-CoA, which is necessary for the
synthesis of fatty acids.
D) Glucose is required for the anaerobic production of ATP. - Answer-A) The synthesis
of triacylglycerols requires glycerol 3-phosphate, which is derived from glucose.

, Which of the following is NOT true of the reaction catalyzed by acetyl-CoA carboxylase?
A) The reaction requires CO2 (or HCO3-).
B) The reaction is inhibited by palmitoyl-CoA
C) The reaction requires one mole of ATP per mole of acetyl-CoA.
D) The reaction is a reduction reaction, which bypasses an irreversible reaction in β-
oxidation. - Answer-D) The reaction is a reduction reaction, which bypasses an
irreversible reaction in β-oxidation.

Which of the following statements is NOT true about energy metabolism and the liver?
A) The liver provides glucose in the blood in response to a glucagon signal.
B) The liver maintains a glycogen store that is replenished after a meal.
C) The liver maintains suitable levels of fuel molecules in the blood for use by other
tissues.
D) The liver releases fatty acids for other tissues to use as fuel. - Answer-D) The liver
releases fatty acids for other tissues to use as fuel.

In an attempt to lose weight, many people follow a high fat, high protein, low
carbohydrate diet. Which of the following substances would NOT have an increased
concentration in the blood after
two weeks on this diet?
A) fatty acids B) ketone bodies C) insulin D) amino acids E) urea - Answer-C) insulin

4-aminobutyrate (GABA, below) is one of the principal inhibitory neurotransmitters of the
mammalian nervous system. It is synthesized in a single step from which amino acid?

A) Arg B) Lys C) Glu D) Asn E) Gln - Answer-C) Glu

Which carbons in fat, if any, can be converted to glucose?
A) Certain carbons from odd chain fatty acids.
B) Carbons from the glycerol backbone.
C) Carbons from the glycerol backbone and certain carbons from odd chain fatty acids.
D) None. - Answer-C) Carbons from the glycerol backbone and certain carbons from
odd chain fatty acids.

Which of the following is associated with the release of insulin from the pancreas?
A) Gluconeogenesis is activated and glycolysis is inhibited.
B) Liver glycogen phosphorylase is activated.
C) Acetyl-CoA levels rise and ketone body synthesis increases.
D) The production of mevalonate decreases.
E) Oxaloacetate levels are high and citrate synthesis increases. - Answer-E)
Oxaloacetate levels are high and citrate synthesis increases.

Familial hypercholesterolemia is associated with a deficiency of which of the following?
A) HDL receptor protein
D) Triacylglycerol lipase
B) LDL receptor protein

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