BCHM 307 - All Questions100% Solved with Verified Solutions
5 keer bekeken 0 keer verkocht
Vak
BCHM 307
Instelling
BCHM 307
Which of the following is true regarding heparin? - Answer -it is used clinically as an
anticoagulant
-it simultaneously binds to antithrombin and the target of antithrombin
-it is a sulfated polysaccharide
-it is an allosteric activator of antithrombin
If an enzyme-catalyzed reaction has a ve...
BCHM 307 - All Questions100% Solved with
Verified Solutions
Which of the following is true regarding heparin? - Answer -it is used clinically as an
anticoagulant
-it simultaneously binds to antithrombin and the target of antithrombin
-it is a sulfated polysaccharide
-it is an allosteric activator of antithrombin
If an enzyme-catalyzed reaction has a velocity of 2 mM/min and a Vmax of 10 mM/min
when the substrate concentration is 0.5 mM, what is the Km? - Answer 2 mM
How are the kinetics of an enzyme-catalyzed reaction affected by a purely
noncompetitive inhibitor? - Answer Vmax decreased, KM unchanged
If a Lineweaver-Burk plot gave a line with an equation of y = 0.490 x + 0.059, what is the
velocity at a substrate concentration of 5 mM? The original units for substrate were in
mM and velocity in mM/s. - Answer 6.37 mM/s
Which of the following properly expresses the Michaelis-Menten equation? - Answer vo
= Vmax [S] / (Km + [S])
How is an enzyme-catalyzed reaction affected by the addition of more enzyme? -
Answer velocity will increase
Which of the following is true regarding transition state analogs? - Answer -they are
competitive inhibitors
-they bind to an active site with much higher affinity than most inhibitors
, -they are much more stable than the transition state
-their affinity for an enzyme is often much greater that the substrate
A Lineweaver-Burk plot is a _____. - Answer double reciprocal plot
If a Lineweaver-Burk plot was made for an enzyme-catalyzed reaction, both with and
without a competitive inhibitor present, what difference would be seen? - Answer the
slope would be less for the inhibited reaction
A plot of velocity versus substrate concentration for a simple enzyme-catalyzed reaction
produces a _____. This indicates that at some point, the enzyme is _____. - Answer
hyperbolic curve; saturated with substrate
An inhibitor that binds to the active site only in the absence of the substrate and in a
reversible fashion is a(n) _____. - Answer competitive inhibitor
How are the kinetics of an enzyme-catalyzed reaction affected by a competitive
inhibitor? - Answer Vmax unchanged, Km increased
An extremely efficient enzyme has a _____ Km and a _____ kcat. - Answer small; large
Some irreversible inhibitors are called _____ because they bind to the active site of the
enzyme and begin the catalytic process, just like a normal substrate. - Answer suicide
substrates
The catalytic constant, or kcat, is also known as the _____. - Answer turnover number
When a substrate and enzyme interact, the first chemical species formed is _____. -
Answer enzyme-substrate complex
Voordelen van het kopen van samenvattingen bij Stuvia op een rij:
Verzekerd van kwaliteit door reviews
Stuvia-klanten hebben meer dan 700.000 samenvattingen beoordeeld. Zo weet je zeker dat je de beste documenten koopt!
Snel en makkelijk kopen
Je betaalt supersnel en eenmalig met iDeal, creditcard of Stuvia-tegoed voor de samenvatting. Zonder lidmaatschap.
Focus op de essentie
Samenvattingen worden geschreven voor en door anderen. Daarom zijn de samenvattingen altijd betrouwbaar en actueel. Zo kom je snel tot de kern!
Veelgestelde vragen
Wat krijg ik als ik dit document koop?
Je krijgt een PDF, die direct beschikbaar is na je aankoop. Het gekochte document is altijd, overal en oneindig toegankelijk via je profiel.
Tevredenheidsgarantie: hoe werkt dat?
Onze tevredenheidsgarantie zorgt ervoor dat je altijd een studiedocument vindt dat goed bij je past. Je vult een formulier in en onze klantenservice regelt de rest.
Van wie koop ik deze samenvatting?
Stuvia is een marktplaats, je koop dit document dus niet van ons, maar van verkoper Examsplug. Stuvia faciliteert de betaling aan de verkoper.
Zit ik meteen vast aan een abonnement?
Nee, je koopt alleen deze samenvatting voor €12,83. Je zit daarna nergens aan vast.
