NSG 552 PSYCHOPHARMACOLOGY EXAM 1,2 & 3 BUNDLE
LATEST ACTUAL EXAM QUESTIONS AND CORRECT DETAILED
ANSWERS
The study of the use of psychotropic medications in the treatment of psychiatric
disorders: - ANSWER: Psychopharmacology
The study of what the body does to drugs: - ANSWER: Pharmacokinetics
The study of what the drugs does to the body: - ANSWER: Pharmacodynamics
Involves the absorption, distribution, metabolism and excretion of meds: - ANSWER:
First Pass Metabolism (C.Y.P. 450)
Increase serum levels of other drugs that are substrates of that enzyme: - ANSWER:
Enzyme inhibitors will slow down metabolism causing toxic levels
Decreases serum levels of other drugs that are substrates of that enzyme: -
ANSWER: Enzyme inducers cause fast metabolism and create subtherapeutic drug
levels
Part of the brain that regulates powerful emotions such as fear, rage, sexual desires:
- ANSWER: Amygdala
The relay station for sensory information: - ANSWER: Thalamus
Essential for maintaining homeostasis, controls basic needs such as sleep- wake
cycles: - ANSWER: Hypothalamus
This lobe is involved in executive functioning, high order planning, speech and
motivation: - ANSWER: Frontal Lobe/ Prefrontal cortex
Derived from Tryptophan and made in the Ralphe Nuclei: - ANSWER: Serotonin
Made in the Locus Ceruleus and involved in the noradrenergic pathways: - ANSWER:
Norepinephrine
90% of serotonin receptors are found in the: - ANSWER: GI tract
Produced in the V.T.A. (Reward Pathway) and involved in the four major pathways: -
ANSWER: Dopamine
Dopamine inhibits prolactin in this pathway: - ANSWER: Tuberoinfundibular
, Increase dopamine in this pathway is associated with positive symptoms: - ANSWER:
Mesolimbic Pathway
Decrease dopamine in this pathway is associated with negative symptoms: -
ANSWER: Mesocortical Pathway
Decrease dopamine in this pathway produces motor symptoms: - ANSWER:
Nigrostriatal Pathway
Main inhibitory neurotransmitter that induces calmness and relaxation: - ANSWER:
Gamma- aminobutyric acid (GABA), Off switch
Main excitatory neurotransmitter: - ANSWER: Glutamate, On Switch
Major organ that breaks down drugs in the body: - ANSWER: Liver
The time needed to clear 50% if drugs from the plasma: - ANSWER: Half-life
The process of becoming desensitized and less responsive to a particular medication
dose overtime necessitating an increase: - ANSWER: Tolerance
A ration describing toxic dose to effective dose: - ANSWER: Therapeutic Index
A chemical that binds to a receptor to produce a biologic response: - ANSWER:
Agonist
A chemical that binds to a receptor but does not fully activate the receptor: -
ANSWER: Partial Agonist
A chemical that binds to a receptor, blocking it to inhibit a biologic response: -
ANSWER: Antagonist
An agent that binds to the same receptor as an agonist but induces an opposite
biological response: - ANSWER: Inverse Agonist
A usually undesired but foreseeable effect that occurs regardless of dose and often
resolves after continued therapy: - ANSWER: Side Effects
S/S opposite of what it was meant to treat: - ANSWER: Paradoxical Reaction
The four main dopamine pathways: - ANSWER: Mesolimbic, mesocortical,
nigrostriatal, tuberoinfundibular
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