100% tevredenheidsgarantie Direct beschikbaar na je betaling Lees online óf als PDF Geen vaste maandelijkse kosten
logo-home
Eerder door jou gezocht
Eerder door jou gezocht
logo
NROB60 FINAL NOTES Exam Questions With 100% Verified Answers €10,96
In winkelwagen
Snel navigeren naar
Voorbeeld
  2.  
  3. NROb60
  4.  
  5. NROb60

Tentamen (uitwerkingen)

NROB60 FINAL NOTES Exam Questions With 100% Verified Answers
 0 keer verkocht
  • Vak
  • NROb60
  • Instelling
  • NROb60

NROB60 FINAL NOTES Exam Questions With 100% Verified Answers Properties of the action potential - answerrising phase overshoot falling phase undershoot What happens when the current reaches threshold? - answergenerate APs at a low rate What happens when current increase? - answerrate of AP g...

[Meer zien]

Voorbeeld 4 van de 38  pagina's

Document informatie

  • 1 oktober 2024
  • 38
  • 2024/2025
  • Tentamen (uitwerkingen)
  • Vragen en antwoorden

Onderwerpen

  • nrob60 final notes exam questions with 100 verifi

Geschreven voor

  • NROb60
  • NROb60

Verkoper

avatar-seller
Brainbarter

Ontvangen beoordelingen

Voorbeeld van de inhoud

©BRAINBARTER 2024/2025




NROB60 FINAL NOTES Exam Questions
With 100% Verified Answers



Properties of the action potential - answer✔rising phase
overshoot
falling phase
undershoot

What happens when the current reaches threshold? - answer✔generate APs at a low rate

What happens when current increase? - answer✔rate of AP generation increases


increases the frequency of AP (all or none situation)

What does the firing frequency of APs reflect? - answer✔the magnitude of the DEPOLARIZING
current


(since hyperpolarizing would not allow threshold to be reached)

What is one way stimulation intensity is encoded? - answer✔firing frequency

What causes ionic changes? - answer✔depolarization causes increase in Na permeability by
opening gates in pores or ion channels

hyperpolarization - answer✔more negative

depolarization - answer✔more positive

what kind of current does the firing frequency reflect? - answer✔depolarizing current
(hyper polarization would not allow threshold to be reached)

, ©BRAINBARTER 2024/2025


How can you flip the membrane potential? - answer✔by changing the relative ionic permeability
of the membrane


rising phase --> have inward Na+ current


falling phase --> has outward K+ current


AP occurs during sudden shift in membrane properties

How does the permeability of the membrane change for AP? - answer✔membrane changes from
K permeability to Na permeability to K permeability

how are interneurons depolarized? - answer✔entry of Na+ through channels that are sensitive to
NT released by other neurons

What are the two types of channels? - answer✔voltage gated
ligand gated

Voltage gated channels - answer✔depends on a change in voltage in order to open and close

ligand gated channels - answer✔ex. needs a neurotransmitter in order to open/close

When is an AP generated? - answer✔if the depolarizing stimulus passes the threshol

Resting potential - answer✔only leak potassium channels are open (these are constantly in an
open state)

Rising Phase - answer✔more and more sodium channels open (driving force of sodium ions
rushing in)


entry of Na+ (usually because Na+ channels are sensitive to membrane stretching)


sodium influx

Overshoot phase - answer✔most positive state


two processes occur simultaneously:

, ©BRAINBARTER 2024/2025


- sodium gates begin to close
- K channels begin to open (these channels differ from leak potassium channels)


because the relative permeability of the membrane favours Na --> membrane potential
approached Ena which is GREATER than 0 mV

Falling phase - answer✔activation of voltage gated potassium channels are AT MAXIMUM


Na channels are mostly al closed


Potassium efflux

Undershoot phase - answer✔hyperpolarization occurs


membrane potential returns to normal


potassium channels (not LEAK ONES) close


little Na permeability and membrane approached Ek --> causes hyperpolarization relative to
RMP until the VG K channels close again

Which channel opens and closes faster? - answer✔Na

Structure of voltage gated sodium channel - answer✔one single long peptide with 4 distinct
domains

what does one domain of voltage gated sodium channel have? - answer✔6 transmembrane alpha
helices


pore loop --> where the ions can move across

Which alpha helix is the voltage sensor? - answer✔S4


consists of regularly spaced positively charged AAs

, ©BRAINBARTER 2024/2025




they react to changes in polarization of the membrane
- depolarization twists the S4 and this change in the molecule causes the gate to open

What makes the channel more permeable to Na+ ? - answer✔selectivity filter

selectivity filter - answer✔for Na channel:
- partially hydrated Na+ can fit through the pore but the partially hydrated K+ ion cannot since it
is TOO BIG

Functional properties of Na+ Channel - answer✔- threshold open up the sodium channel and
sodium can rush in
(open almost immediately)


- stays open for about 1msec then inactivates (Mg 2+ blocks it ) --> after Na+ rushes in
(this rapid opening of channels in response to depolarization explains the rising phase)


- cannot open again until voltage reduces to below threshold


- another AP cannot be generated until the channels are activated

Tetrodotoxin - answer✔could selectively block Na channel


clogs the Na permeable pore by binding tightly to a specific site on the OUTSIDE OF THE
CHANNEL

Saxitoxin - answer✔another Na+ channel blocking toxin


concentrated in clams, mussels, and other shellfish that feed on these organisms


marine protozoa

Batrachotoxin - answer✔- causes the channels to open at more negative potentials and to stay
open much longer than usual

Dit zijn jouw voordelen als je samenvattingen koopt bij Stuvia:

Bewezen kwaliteit door reviews

Bewezen kwaliteit door reviews

Studenten hebben al meer dan 850.000 samenvattingen beoordeeld. Zo weet jij zeker dat je de beste keuze maakt!

In een paar klikken geregeld

In een paar klikken geregeld

Geen gedoe — betaal gewoon eenmalig met iDeal, creditcard of je Stuvia-tegoed en je bent klaar. Geen abonnement nodig.

Direct to-the-point

Direct to-the-point

Studenten maken samenvattingen voor studenten. Dat betekent: actuele inhoud waar jij écht wat aan hebt. Geen overbodige details!

Veelgestelde vragen

Wat krijg ik als ik dit document koop?

Je krijgt een PDF, die direct beschikbaar is na je aankoop. Het gekochte document is altijd, overal en oneindig toegankelijk via je profiel.

Tevredenheidsgarantie: hoe werkt dat?

Onze tevredenheidsgarantie zorgt ervoor dat je altijd een studiedocument vindt dat goed bij je past. Je vult een formulier in en onze klantenservice regelt de rest.

Van wie koop ik deze samenvatting?

Stuvia is een marktplaats, je koop dit document dus niet van ons, maar van verkoper Brainbarter. Stuvia faciliteert de betaling aan de verkoper.

Zit ik meteen vast aan een abonnement?

Nee, je koopt alleen deze samenvatting voor €10,96. Je zit daarna nergens aan vast.

Is Stuvia te vertrouwen?

4,6 sterren op Google & Trustpilot (+1000 reviews)

Afgelopen 30 dagen zijn er 71250 samenvattingen verkocht

Opgericht in 2010, al 15 jaar dé plek om samenvattingen te kopen

Begin nu gratis

Laatst bekeken door jou

Tentamen (uitwerkingen) ·

(1)

Texas Roadhouse Menu Test Key Questions and Answers Rated A+

Case uitwerking ·

(0)

NR 305 Week 8 Discussion Topic, Rapid Assessment of a Client

Tentamen (uitwerkingen) ·

(0)

DC Permit Test Questions And 100% Accurate Verified Answers.

Tentamen (uitwerkingen) ·

(0)

Idaho real estate test questions and answers already passed

Samenvatting ·

(0)

VWO 3, H3 scheikunde samenvatting van boek: chemie 7e editie.

Overig ·

(0)

BYE BYE BARCELONA (2014). Estructura de mercados. Turismo UAM

Tentamen (uitwerkingen) ·

(0)

Aceable Agent state exam study set with 100% correct answers

Tentamen (uitwerkingen) ·

(0)

BIO 446L-Female Reproductive System Questions and Correct Answers

Tentamen (uitwerkingen) ·

(0)

MBAE 6865 Chapter 6 Quiz 100% Complete Questions and Answers

€10,96
  • (0)
In winkelwagen
Toegevoegd