Psoriasis: The Basics - Answer-- chronic multisystem disease with predominantly skin and joint manifestations
- Affects approximately 2% of the U.S. population
- Age of onset occurs in two peaks: ages 20-30 and ages 50-60, but can be seen at any age
- There is a strong genetic component
- About...
Psoriasis Exam Questions with Verified
Answers
Psoriasis: The Basics - Answer-- chronic multisystem disease with predominantly skin
and joint manifestations
- Affects approximately 2% of the U.S. population
- Age of onset occurs in two peaks: ages 20-30 and ages 50-60, but can be seen at any
age
- There is a strong genetic component
- About 30% of patients with psoriasis have a first-degree relative with the disease
- Waxes and wanes during a patient's lifetime, is often modified by treatment initiation
and cessation and has few spontaneous remissions
Classification of Psoriasis
is based on morphology - Answer-- plaque
- inverse/flexural
- guttate
- erythrodermic
- pustular
- Clinical findings in patients frequently overlap in more than one category
- Different types of psoriasis may require different treatment
Plaque - Answer-scaly, erythematous patches, papules, and plaques that are
sometimes pruritic
Inverse/flexural - Answer-lesions are located in the skin folds
Guttate - Answer-presents with drop lesions, 1-10mm salmon-pink papules with a fine
scale
Eryhtrodermic - Answer-generalized erythema covering nearly the entire body surface
area with varying degrees of scaling
Pustular - Answer-- clinically apparent pustules
- Rare, acute generalized variety called "von Zumbusch variant"
- Palmoplantar - localized involving palms and soles
Guttate Psoriasis - Answer-- Acute onset of raindrop-sized lesions on the trunk and
extremities
- Often preceded by streptococcal pharyngitis
Inverse/Flexural Psoriasis - Answer-- Erythematous plaques in the axilla, groin,
inframammary region, and other skin folds
- May lack scale due to moistness of area
, Pustular Psoriasis - Answer-- Characterized by psoriatic lesions with pustules.
- Often triggered by corticosteroid withdrawal.
- When generalized, pustular psoriasis can be life-threatening.
- These patients should be hospitalized and a dermatologist consulted.
Palmoplantar Psoriasis - Answer-- May occur as either plaque type or pustular type.
- Often very functionally disabling for the patient.
- The skin lesions of reactive arthritis typically occur on the palms and soles and are
indistinguishable from this form of psoriasis.
Psoriatic Erythroderma - Answer-- Involves almost the entire skin surface; skin is bright
red
- Associated with fever, chills, and malaise
- Like pustular psoriasis, hospitalization is sometimes required
Plaque Psoriasis - Answer-- Well-demarcated plaques with overlying silvery scale and
underlying erythema
- Chronic plaque psoriasis is typically symmetric and bilateral
- Plaques may exhibit:
a. Auspitz sign (bleeding after removal of scale)
b. Koebner phenomenon (lesions induced by trauma
Plaque Psoriasis: The Basics - Answer-- is the most common form, affecting 80-90% of
patients
- Approximately 80% of patients with plaque psoriasis have mild to moderate disease -
localized or scattered lesions covering less than 5% of the body surface area (BSA)
- 20% have moderate to severe disease affecting more than 5% of the BSA or affecting
crucial body areas such as the hands, feet, face, or genitals
Psoriasis: Pathogenesis - Answer-- Psoriasis is a hyperproliferative state resulting in
thick skin and excess scale
- Skin proliferation is caused by cytokines released by immune cells
- Systemic treatments of psoriasis target these cytokines and immune cells
Ask About Past Medical History for Psoriasis - Answer-- Psoriasis can be triggered by
infections, especially streptococcal pharyngitis
- Psoriasis can be more severe in patients with HIV
- Up to 20% of psoriasis patients have psoriatic arthritis, which can lead to joint
destruction
- There is a positive correlation between increased BMI and both prevalence and
severity of psoriasis
- Patients with psoriasis may have an increased risk for cardiovascular disease and
should be encouraged to address their modifiable cardiovascular risk factors
- also family history, meds, & social history
Voordelen van het kopen van samenvattingen bij Stuvia op een rij:
Verzekerd van kwaliteit door reviews
Stuvia-klanten hebben meer dan 700.000 samenvattingen beoordeeld. Zo weet je zeker dat je de beste documenten koopt!
Snel en makkelijk kopen
Je betaalt supersnel en eenmalig met iDeal, creditcard of Stuvia-tegoed voor de samenvatting. Zonder lidmaatschap.
Focus op de essentie
Samenvattingen worden geschreven voor en door anderen. Daarom zijn de samenvattingen altijd betrouwbaar en actueel. Zo kom je snel tot de kern!
Veelgestelde vragen
Wat krijg ik als ik dit document koop?
Je krijgt een PDF, die direct beschikbaar is na je aankoop. Het gekochte document is altijd, overal en oneindig toegankelijk via je profiel.
Tevredenheidsgarantie: hoe werkt dat?
Onze tevredenheidsgarantie zorgt ervoor dat je altijd een studiedocument vindt dat goed bij je past. Je vult een formulier in en onze klantenservice regelt de rest.
Van wie koop ik deze samenvatting?
Stuvia is een marktplaats, je koop dit document dus niet van ons, maar van verkoper lectknancy. Stuvia faciliteert de betaling aan de verkoper.
Zit ik meteen vast aan een abonnement?
Nee, je koopt alleen deze samenvatting voor €12,33. Je zit daarna nergens aan vast.
