IMM250 EXAM QUESTIONS AND CORRECT ANSWERS (ALREADY GRADED A+)
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IMM250
IMM250 EXAM QUESTIONS AND CORRECT ANSWERS (ALREADY GRADED A+)
Which of the following changes is seen at infected sites as a consequence of an acute inflammatory response: - Answer- 1. Recruitment of neutrophils
2. Increased expression of cell adhesion molecules on endothelial cells
3. Edema
4. ...
IMM250 EXAM QUESTIONS AND
CORRECT ANSWERS (ALREADY
GRADED A+)
Which of the following changes is seen at infected sites as a consequence of an acute
inflammatory response: - Answer- 1. Recruitment of neutrophils
2. Increased expression of cell adhesion molecules on endothelial cells
3. Edema
4. Increased vascular permeability
CRP (C-reactive protein) - Answer- 1. An indicator of infection
2. A PRR
3. An opsonin
4. A protein that can activate complement
5. produced in response to IL-6
Type I IFNs - Answer- 1. They induce the synthesis of enzymes that degrade viral RNA
2. Their production is regulated by transcription factors called IRFs
3. The Type I IFN receptor is ubiquitously expressed
What is true about primary and secondary lymphoid tissues? - Answer- Primary
lymphoid tissues are sites where lymphocytes mature from precursor cells
Secondary lymphoid tissues are sites where mature lymphocytes are activated by
specific antigen
matching of lymphocyte antigen receptor with their properties - Answer- TCR-no
secreted form
BCR-has two antigen binding sites
BCR/TCR-both have variable and constant regions & don't recognize PAMPs
Which best describes the antigen receptors on the cell surface of a lymphocyte? -
Answer- There are many copies of one receptor protein that can bind a single antigen
"A mechanism known as [blank 1] is responsible for the [blank 2] of lymphocyte antigen
receptors, and affects the protein structure of the [blank 3] region of these molecules. " -
Answer- "A mechanism known as gene rearrangement is responsible for the diversity of
lymphocyte antigen receptors, and affects the protein structure of the variable region of
these molecules. "
, Clonal selection involves the idea that: - Answer- Only a lymphocyte clone with a
complementary antigen receptor will be activated by a particular antigen
When a mature lymphocyte is called 'naïve' it is because: - Answer- It has not yet
encountered antigen
Which represents the correct order of steps in lymphocyte activation? - Answer- Antigen
receptor signaling, Costimulatory signaling, Cytokine signaling
Immature dendritic cells are: - Answer- Not very mobile
Consider the following events ('a' through 'd') that occur at some point during an
adaptive immune response:
a) Clonal expansion and differentiation of antigen-specific T cells
b) Th and CTL are reactivated by specific antigen and perform clearance functions
c) Effector lymphocytes travel to inflamed tissue
d) Costimulation between mature DC and naive T cells
Which sequence below represents the order in which these events occur? - Answer-
1)Costimulation between mature DC and naive T cells
2)Clonal expansion and differentiation of antigen-specific T cells
3)Effector lymphocytes travel to inflamed tissue
4)Th and CTL are reactivated by specific antigen and perform clearance functions
Ilya Mechnikov - Answer- cellular immunology
Paul Ehrlich - Answer- humoral immunology
Louis Pasteur - Answer- 1. fermentation as a process caused by microorganisms
2. the disproval of spontaneous generation of microorganisms
3. the first rabies vaccine(the first cholera vaccine)--> innoculated a person with the
rabies vaccine
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