Rheumatology MCQ Test Questions and Answers 2025
A 22-year-old runner was referred to Rheumatology department with medial left knee pain for 6
months. The pain is worsened running, by going up stairs and by sleeping on either side at night.
On examination, there is localized tenderness on the lower medial aspect of the left knee. There
is no joint line tenderness or swelling. X-ray of the left knee (PA and sky line view) is
unremarkable.
1. What is the most likely cause of her symptoms?
A. Osteoarthritis of the patella-femoral joint
B. Pes Anserinus Bursitis
C. Patellofemoral Syndrome
D. Hamstring Strain
E. Prepatellar Bursitis
2. A 35 year old female who has recently started to train for a
marathon presents with left hip pain. This is over the lateral side
of her hip and radiates down her thigh and is worse when she lies
on it at night. On examination there is tenderness over the greater
trochanter and the pain reproduced by external rotation. What is
the most likely diagnosis?
Impacted hip fracture
Soft Tissue Injury
Osteoarthritis
Avascular Necrosis
Trochanteric Bursitis
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2. What organism most commonly leads to septic arthritis?
A. Staph. Aureus
B. Strep. Epidermidis
C. H. Influenzae
D. N. Gonorrhoea
E. MRSA
3. 69 year old female with a previous history of rheumatoid arthritis, currently on
methotrexate, presents with painful, swelling of her right knee. She is also pyrexial and
generally unwell. What is the most likely diagnosis?
A. Septic Arthritis
B. Gout
C. Pseudogout
D. Osteoarthritis
E. Flair of Rheumatoid Arthritis
A.
A 17-year-old sexually active adolescent male presents with a 5-day
history of fever, chills, and persistent left ankle pain and swelling. On
physical examination, maculopapular and pustular skin lesions are
noted on the trunk and extremities. He denies any symptoms of genitourinary
tract infection. Synovial fluid analysis is most likely to show
which of the following?
A. WBCs 75,000/mm 3 with 95% polymorphonuclear leukocytes
B. RBCs 100,000/mm 3 , WBCs 1000/mm3
C. WBCs 48,000/mm 3 with 80% lymphocytes
D. WBCs 500/mm 3 with 25% polymorphonuclear leukocytes
Answer A
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A 52 year old woman with previous history of IBS presents with
general aches and pains all over with stiffness in her hands and
wrist, not worse at any time of the day. She has been unable to
sleep because of the pain and is very fatigued. She is also
suffering from band like headaches. On examination there are
multiple tender spots over her hips and back. Blood results
including auto antibodies are normal. What is the most likely
diagnosis?
IBS
Rheumatoid Arthritis
Depression
Fibromyalgia syndrome
Chronic fatigue syndrome
A 35 year old female with rheumatoid arthritis presents with pain
and tightness behind of the left leg. On examination there is
evidence of a swelling in behind the ankle . What investigation
should be organised?
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, 4
Arthroscopy
Routine bloods
MRI of knee
Ultrasound of popliteal fossa
d-dimers
In septic arthritis:
a) Bone scan is positive
b) Gallium scan is positive
c) Instillation of antibiotics into joint space is the most effective
method of treatment
d) Surgical drainage is indicated in the hip joint
e) Joint fluid culture is frequently negative in gonococcal
arthritis
5. A 7 year old boy l is generally unwell and his temperature is hight, he is
also unable to weight bear due to hip pain. Her inflammatory markers are
markedly raised. An X-ray shows a widened joint space. e. What is the
most likely diagnosis?
A. Osteomyelitis
B. Perthes disease
C. Slipped upper femoral epiphysis
D. Non-accidental injury
E. Septic arthritis
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