CSB520 Questions and Correct Answers the Latest Update
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What is apoptosis?
- Process of programmed cell death that is not reversible
-Active process that requires energy
-Can be pathological or physiological
-Can occur in single cells
What is necrosis?
-Sudden cell death that is not reversible
-Passive process that does not require energy
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CSB520 Questions and Correct Answers
the Latest Update
What is apoptosis?
✓ - Process of programmed cell death that is not reversible
✓ -Active process that requires energy
✓ -Can be pathological or physiological
✓ -Can occur in single cells
What is necrosis?
✓ -Sudden cell death that is not reversible
✓ -Passive process that does not require energy
✓ -Pathological
✓ -Impossible for a single cell to die via necrosis as it also kills neighbouring cells
✓ -Stimulates inflammation
What does the type of cell death depend on?
✓ Depends on the severity and duration of the stressor and how health the
cell was to begin with
What is an infarct?
✓ An area of necrotic tissue that occurs through irreversible injury usually
sudden in nature
What determines whether a stimulus causes atrophy or infarction?
✓ 1. Cell/Tissue Type
✓ 2. Cell history
✓ 3. Stimuli
✓ 4. Severity and duration
What effect does ageing have on cells and organs
✓ - Autophagy ability declines with age
✓ -Defective removal of damaged mitochondria results in increased free radical
generation
✓ -Therefore increased stressors often result in apoptosis or necrosis of the cell
What is hyperplasia?
✓ Increase in cell number if tissue is labile or stable
What is hypertrophy?
✓ Increase in cell size
What cellular adaptations lead to an increase in the overall size of an organ?
✓ Hyperplasia and Hypertrophy
What form of cell death occurs during normal embryogenesis?
✓ The change from one normal adult or well differentiated cell type into
another normal adult or well-differentiated cell type
How does necrosis cause inflammation?
✓ During necrosis the cell lyses so the contents of the cell spill out killing
surrounding cells & stimulating an inflammatory response.
Does metaplasia alter the function(s) of the cells & is metaplasia reversible?
✓ Yes structure & function are linked so when the structure or cell type
changes so does the cells capabilities. Metaplasia is a reversible
adaptation.
What is autophagy?
✓ Cell shrinkage through self-eating
What is atrophy?
✓ decrease in cell size
How does atrophy differ between young and elderly tissues?
✓ In young healthy tissues that are subjected to stress, cells will often
choose to shrink through autophagy whereas as we age the ability for our
cells to undergo autophagy declines meaning that cells are more likely to
undergo apoptosis
What are three types of cells? With examples of each cell type
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