Karch's Focus on Pharmacology 8th Ed. | Chapter 1 2024
1. Clinical Pharmacology: the study of drugs used to treat, prevent, or
diagnose disease.
2. Phase I drug studies involve: healthy human volunteers who are often paid
for their participation.
3. The generic name of a drug is: the original name assigned to the drug at
the beginning of the evaluation process.
4. An orphan drug is a drug that: has been tested but is not considered to be
financially viable.
5. The FDA pregnancy categories were used: to indicate a drug's potential or
actual teratogenic effects.
6. The storing, prescribing, and distributing of controlled substances -
drugs that are more apt to be addictive - are monitored by: the DEA.
7. Healthy young women are not usually involved in phase I studies of
drugs because: females are more apt to suffer problems with ova, which are
formed only before birth.
8. A patient has been taking fluoxetine (Prozac) for several years, but
when picking up the prescription this month found that the tablets looked
different and became concerned. The nurse, checking with the pharmacist,
found that fluoxetine had just become available in the generic form and the
prescription had been filled with the generic product. The nurse should tell
the patient: that the law requires that prescriptions be filled with the generic form
if available to cut down the cost of medications.
9. When teaching a patient about OTC drugs, which points should the
nurse include?: c. Many of these drugs were once prescription drugs but are now
thought to be safe for use without a prescription when used as directed.
d. Reading the label of these drugs is very important; the name of the active
ingredient is prominent; you should always check the ingredient name.
e. It is important to read the label and to see what the recommended dose of
the drug is; some of these drugs can cause serious problems if too much of the
drug is taken.
f. It is important to report the use of any OTC drug to your healthcare provider
because many of them can interact with drugs that might be prescribed for you.
10. A patient asks what generic drugs are and if he should be using them to
treat his infection. Which of the following statements should be included in
the nurse's explanation?: a. A generic drug is a drug that is sold by the name of
the ingredient, not the brand name.
c. Generic drugs are not available until the patent expires on a specific drug.
d. Generic drugs are usually cheaper than the well-known brand names, and some
insurance companies require that you receive the generic drug if one is
available.
f. Your physician may want you to have the brand name of a drug, not the generic
form, and DAW will be on your prescription form.
11. A nurse is teaching a client about the pharmacotherapeutics of the
hormone replacement therapy that the client has been prescribed. What
topic should the nurse address?: the effect of the drug on the client's body.
12. After teaching a group of students about the responsibilities of the
Food and Drug Administration (FDA) related to drugs, the instructor
determines that the students need additional teaching when they identify
what as a major responsibility?: enforcement of control of substances with high
abuse potential
13. The nurse understands that medications are not just manufactured and
dispensed. How many phases of clinical trials must a drug go through in
order to meet approval standards?: 4
14. Which drugs are examples of Schedule III medications that have accepted
medical use in the United States? Select all that apply.: phenobarbita
chlorphentermine
15. The nurse is reviewing a prescription for a medication with a client. On the
prescription, the nurse read "DAW." What should the nurse teach the
client?: The brand name of the drug must be dispensed.
16. A client asks a nurse whetherover-the-counter drugs have any
disadvantages. What would the nurse cite as potential disadvantages?
(Select all that apply.):\
inaccurate self-diagnoses choosing an incorrect drug
delaying treatment by a health care provider
developing adverse drug reactions
17. A client is started on aripiprazole and the nurse notices the client is
experiencing dry mouth and nasal congestion. What intervention does the
nurse teach the client to minimize the side effects of the medication?:
Drinking frequent sips of water.
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