Cytokine signaling - Samenvattingen, Aantekeningen en Examens

Describe Type I vs Types II interferons? - Type I interferon is secreted when a human cell is infected with a virus, interfere with viral replication, alert immune system cells that an infection is present, make virally infected cells more vulnerable to killer lymphocyte attack, Type I interferon inducing proliferation of NK cells, Type II interferon (interferon gamma) secreted from NK cells, CD8T cells and CD4 TH1 cells What cells can produce Type I interferon? - Almost all nucleated cells...

MCB 150 Midterm 3 Questions and Answers Latest 2024 Issues for vaccine design - antigenic variation/drift: viruses have different antigenic subtypes and some have high mutation rates - prevent potential pathogenesis: vaccines must not cause excess immune pathology; some vaccine trials result in worse disease antibody dependent enhancement (ADE) a vaccine makes the infection worse instead of preventing it inflammation a nonspecific response mediated by cytokines, small mole...

Affinity Maturation - Answer-spontaneous mutations of antibody genes in activated B-cells leading to antibodies with better binding capacity of the antigen Hematopoiesis - Answer-The generation of blood cells Ig M - Answer-This type of antibody appears first in an immune response Site of hematopoiesis - Answer-Bone Marrow Interferon - Answer-Cytokine that shuts down or kills virus infected cells Neutralization - Answer-antibodies bind to a toxin rendering it harmless Class Swit...

Combined Immunology HMX Exam with 100% Correct Answers 2024/2025. Individuals who are not identical twins differ in many genes that they do not inherit. This means individuals will have different proteins based on these different genes. These differences are called ______________________ - Correct Answer-polymorphisms In transplantation, if one person is a donor and another is a recipient, then there might be a difference in proteins between each person. So, when an organ is transplanted, t...

IHS 340 Practice Exam 100% REVISION 2023//2024 Dendritic cells present extracellular-acquired antigen to which type of cell? A) epithelial cells B) mast cell C) B cell D) T cell E) macrophage - ANSWER D) t cell Which of the following is NOT a characteristic of a cytokine? (A) it is a protein produced by infectious agents, such as bacteria (B) it binds to a specific receptor on host cells (C) it is an intercellular signaling molecule (D) it can act locally or systemically (E) it ...

Immunology Exam 1 - BIOL 5500 combatting multicellular parasites or helminths What are the major function of eosinophils? source of cytokine IL-4 which INITIATES allergic response What is the major function of Basophils? Major mediators of CARRYING OUT allergic reactions What is the major function of mast cells? basophils and mast cells Which two granulocytes have the most in common? 24 hours What is the half life of a neutrophil? neutrophils Which granulocyte is ...

RECEPTOR ON CELL PROLIFERATION Mutations in the receptor were made to evaluate the roles of various tyrosine residues in receptor function (Roussel and Sherr, 1993; Roussel, 1994). Remarkably, the deletion of the kinase insert did not have any significant effect on the ability of the cell to respond to CSF-1, suggesting that the binding of all of the partners to the phosphorylated tyrosines in that domain was not essential for CSF-1-dependent proliferation. However, the substitution of ...

NSG5003 MIDTERM EXAM QUESTIONS AND ANSWERS Acoustic trauma and noise-induced hearing loss is associated with what? - ANSWER noise A hypersensitivity reaction that produces an allergic response is called what? - ANSWER Anaphylaxis Which cytokine is produced and released from virally infected host cells? - ANSWER Interferon-alpha (IFN-a) Which T-lymphocyte phenotype is the key determinant of childhood asthma? - ANSWER CD4 helper T2 lymphocytes Some older adults ha...

NSG 5003 Midterm Exam Questions and Answers Latest Updated 2024 (GRADED A+) What two types of hearing loss are associated with noise? Student Answer: Acoustic trauma and noise induced High frequency and low frequency High frequency and acoustic trauma Noise induced and low frequency Instructor Explanation: Two types of hearing loss are associated with noise: (1) acoustic trauma or instantaneous damage caused by a single sharply rising wave of sound (e.g., gunfire), and (2) noise-induc...

Test Bank for Porth's Essentials of Pathophysiology 5th Edition by Tommie L Norris Test Bank for Porth's Essentials of Pathophysiology 5th edition by Tommie L Norris 1. Chapter 1 Although the basic structure of the cell plasma membrane is formed by a lipid bilayer, most of the specific membrane functions are carried out by: A) Bound and transmembrane proteins B) Complex, long carbohydrate chains C) Surface antigens and hormone receptors D) A gating system of selective ion channels Feedback: Th...