Whole genome sequencing Samenvattingen, Aantekeningen en Examens

MICROBIOLOGY FINAL TEST BANK| COMPREHENSIVE SOLUTIONS UPDATEMICROBIOLOGY FINAL TEST BANK| COMPREHENSIVE SOLUTIONS UPDATE Penicillin controls bacterial growth by: A) preventing synthesis of the lipopolysaccharide layer B) inhibiting protein synthesis C) preventing cross-link formation in peptidoglycan D) preventing generation of the proton motive force preventing cross-link formation in peptidoglycan Reproduction via binary fission leads to what type of growth under optimal conditions: A...

Nucleotide - ANS deoxyribose, a 5C sugar with a hydroxyl group on the 3' carbon and a phosphate group on the 5' carbon, and a nitrogen base attached to the 1' carbon Amino acid - ANS coded 5' to 3' (N terminus to C terminus) Central dogma - ANS describes the flow of information from DNA (genotype) to RNA (portable) to protein (phenotype) via transcription and translation Codon - ANS A specific sequence of three adjacent bases on a strand of DNA o...

Pyrimidine - Answer One carbon ring Cytosine, Thymine, Uracil What is the function of mRNA? - Answer Carries genetic info out of nucleus Transcript translated to protein What is the function of tRNA? - Answer Carries aa to ribosome Anticodon pairs with codon on mRNA strand What is the function of rRNA? - Answer part of ribosome structure most abundant RNA coordinated coupling of tRNA to mRNA codons Feedback inhibition - Answer Product of pathway is noncompetitive inhibitor Binds to all...

Genetic Counseling Boards Review Questions and Answers (summer 2023/24). - A young patient (5yrs) presents for the first time to a new dentist with crowded teeth, making them very hard to clean. In further exploration of the issue, she learns that the child had delayed eruption of his teeth. The patient's mother also relays that her pediatrician has several times noted how prominent the veins of his scalp are and his short stature. However, she thinks that this is just part of the spectrum ...

Nuremberg Code (1947) A research ethics code that arose in response to the Nazis' inhumane experimentation (nuremberg trials) - holocaust, racial hygiene / eugenics / master race. The Nuremberg Code - 10 points 1. voluntary 2. necessary for results 3. logical design and results 4. avoid unnecessary harm 5. cannot result in death or disablement 6. risk assessment 7. protect subjects against harm 8. qualified investigators 9. right to withdrawal 10. right to end trial if needed ...

Three Perspectives that summarize bioinformatics ANS 1. Bioinformatics in the Cell- central dogma DNA to RNA to protein. 2. Tracing order of genes in natural state and how they are regulated across time and region in response to physiological state. 3. Phylogeny and the tree of life What was the real catalyst that increased the number of base pairs of DNA in GeneBank ANS Whole Genome Sequencing What are the major databases containing genomic data? What is the bias? ANS GenBank, D...

Biology B: Exam 3 Questions and Answers Already Passed In pea plants, red flowers and round pollen are known to be recessive traits. In a dihybrid cross experiment, lots of plants with red flowers and round pollen are found in the F2 generation. How is this possible? The genes for flower color and pollen shape are linked. A Punnett square incorrectly predicts the outcome of a dihybrid cross. There are four phenotypes in the F2 offspring, but not in the expected ratios. Why? The genes are parti...

MB (ASCP) Exam Questions and Answers Graded A+ Predominant form of DNA Right-handed B DNA and histone interaction is due to what type of bond? Ionic What stains to the minor groove of DNA duplex? SYBR Green What is the most abundant type of RNA? Ribosomal RNA (rRNA) What does RNA act as in a retrovirus? Genome and mRNA What increases half-life of mRNA? 5' Methyl Cap What kind of DNA is most likely to be transcriptionally active? Euchromatin What is the most common type of eukaryot...

MB (ASCP) Exam Questions and Answers Graded A+ Predominant form of DNA Right-handed B DNA and histone interaction is due to what type of bond? Ionic What stains to the minor groove of DNA duplex? SYBR Green What is the most abundant type of RNA? Ribosomal RNA (rRNA) What does RNA act as in a retrovirus? Genome and mRNA What increases half-life of mRNA? 5' Methyl Cap What kind of DNA is most likely to be transcriptionally active? Euchromatin What is the most common type of eukaryo...

Biological TechniquesTable of contents  Introduction  Fundamentals of NGS  Potential uses of NGS a. Microbiology b. oncology  NGS Methods Genomics a. Whole genome sequencing b. Exome sequencing c. De novo sequencing Transcriptomics a. Total RNA and mRNA sequencing b. Targeted RNA sequencing Epigenomics a. Methylation sequencing  Limitations  References Next generation sequencing Next generation sequencing (NGS), massively parallel or deep sequencing are rela...