Dr watson - Samenvattingen en Aantekeningen

This document contains all elaborations on the cases, lectures and practice exam questions. For this exam, I got an 8.0

What was the date DST was founded? - correct answer January 13, 1913 Where was it founded? And by who? - correct answer It was founded at Howard University by 22 women who were former AKA's Why did the founders of DST leave AKA? - correct answer - They thought that AKA was too much of a social organization and weren't interested in the principles an...

4) Exposure of DNA to oxidizing agents can result in the oxidation of G residues in the DNA resulting in the formation 8-oxoG. This damage is highly mutagenic since 8- oxoG can pair with A, which leads to a G to T transversion mutation. This type of mutation frequently occurs in tumor suppressor genes such as p53 leading to cancer. The 8-oxoG:A H2N basepair has the structure shown on the right. Note that this basepair can only form if the glycosidic bond to the 8-oxoG is in the syn conforma...