Lynch syndrome Samenvattingen, Aantekeningen en Examens
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![Cancer Syndromes for ABGC Boards (100% Correct Answers)](/docpics/3289163/64e4102016b9b_3289163_121_171.jpeg)
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Cancer Syndromes for ABGC Boards (100% Correct Answers)
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HBOC correct answers breast, ovarian, prostate, melanoma 
 
Familial Adenomatous Polyposis correct answers CHRPE (congenital hypertrophy of the retinal pigment epithelium) 
 
Li-Fraumeni correct answers TP53 
Early breast, sarcoma (osteo or soft tissue), brain, leukemia, **adrenocortical carcinoma, **choroid plexus carcinoma (childhood), fam hx childhood onset tumors 
 
Cowden correct answers Folliular Thyroid, Breast, uterine, macrocephaly, Lhermitte-Duclose disease (LDD)= cerebellar dysplastic...
![MB (ASCP) 2022 Already Passed](/docpics/63652d32065e7_2081163.jpg)
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MB (ASCP) 2022 Already Passed
- Tentamen (uitwerkingen) • 28 pagina's • 2022
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MB (ASCP) 2022 Already Passed 
Consider the table below where a child and a possible father (PF) share the listed paternity indices for each locus listed (LOC-A1, LOC-B2, LOC-C3, LOC-D4). Locus Tested PF Child Paternity Index LOC-A1 3 2/3 2.18 LOC-B2 7/5 5 0.798 LOC-C3 15/17 9/17 5.21 LOC-D4 12 12 1.37 Based on the data presented in the table, what is the combined paternity index, CPI, from the loci tested: LOC-A1, LOC-B2, LOC-C3 and LOC-D4? 12.42 9.558 15.56 2.38 12.42 ( CPI is calculated by mu...
![Women's Health III - Gynecologic Cancers correctly answered](/docpics/4720214/65ef4865ee74e_4720214_121_171.jpeg)
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Women's Health III - Gynecologic Cancers correctly answered
- Tentamen (uitwerkingen) • 13 pagina's • 2024
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Women's Health III - Gynecologic Cancers 
When can genetic counseling be done to test for gynecologic cancers? - correct answer - antenatal 
- cardiology 
- cancer 
- 90% of cancer is sporadic 
- 10% is hereditary 
 
What people are at increased risk of gynecologic cancer? - correct answer - Early age of onset 
- Multiple affected family members 
- "Related" cancers in the family (includes pancreatic/prostate) 
- Multiple primaries 
- Unusual presentation 
- Ethnicity = Ashkenazi Jews 
- Pa...
![ABGC Boards - Final Review 2024 (100% Verified with correct answers)](/docpics/4160428/6599f89b907d2_4160428_121_171.jpeg)
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ABGC Boards - Final Review 2024 (100% Verified with correct answers)
- Tentamen (uitwerkingen) • 59 pagina's • 2024
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Hereditary Breast and Ovarian Cancer correct answers BRCA 1/2 
Breast 50-87% 
Second primary tumor 50-64% 
BRCA 1: 20-45% BRCA 2: 10-30% 
BRCA 2: Male breast 6-10% 
 
Li-Fraumeni Syndrome correct answers -Sarcoma, breast, leukemia, adrenal and many others 
-May present in almost every way (ie all family members with same cancers or all with different) 
-Adrenocortical carcinoma considered pathognomonic 
-50% have some type by 30, 90% by age 60 
-TP53 accounts for 70% of individuals 
 
Beckwit...
![MB (ASCP) 2020(updated) correctly answered](/docpics/63996ed93ad87_2178576.jpg)
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MB (ASCP) 2020(updated) correctly answered
- Tentamen (uitwerkingen) • 38 pagina's • 2022
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MB (ASCP) 2020(updated) correctly answeredConsider the table below where a child and a possible father (PF) share the listed paternity indices for each locus listed (LOC-A1, LOC-B2, LOC-C3, LOC-D4). 
 
Locus Tested PF Child Paternity Index 
LOC-A1 3 2/3 2.18 
LOC-B2 7/5 5 0.798 
LOC-C3 15/17 9/17 5.21 
LOC-D4 12 12 1.37 
 
Based on the data presented in the table, what is the combined paternity index, CPI, from the loci tested: LOC-A1, LOC-B2, LOC-C3 and LOC-D4? 
12.42 
9.558 
15.56 
2.38 
12.42...
![WGU D027 Practice Test// (Top 2024/2025 EXAM REVIEW PAPERS / GRADED A+/ 100% Accurate)](/docpics/3768013/65469f158d3eb_3768013_121_171.jpeg)
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WGU D027 Practice Test// (Top 2024/2025 EXAM REVIEW PAPERS / GRADED A+/ 100% Accurate)
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WGU D027 Practice Test 
A patient has endured several dosage adjustments of his tricyclic antidepressant, so the provider 
recommends genetic testing. Which statement correctly describes the rationale for genetic testing? 
a. The CYP2D6 gene influences metabolism of tricyclic antidepressants and certain other drugs. 
b. The HER2 gene is a tumor marker that impacts metabolism of tricyclic antidepressants. 
c. The BRCA2 gene influences metabolism of certain drugs and increases the risk for breast...
![Women's Health- Gynecologic Cancers questions and answers graded A+](/docpics/4720531/65ef4efa84f69_4720531_121_171.jpeg)
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Women's Health- Gynecologic Cancers questions and answers graded A+
- Tentamen (uitwerkingen) • 8 pagina's • 2024
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Women's Health- Gynecologic Cancers 
what are the 2 types of uterine cancer? - correct answer 1. endometrial carcinoma 
2. uterine sarcoma- leiomyosarcoma 
 
which uterine cancer accounts for 95% of all cases? - correct answer endometrial carcinoma 
 
what is endometrial carcinoma? - correct answer cancer of the uterus lining 
 
what is uterine sarcoma? - correct answer cancer of the uterine muscle 
 
what are risk factors for uterine cancer? - correct answer 1. age- average age is 62 
2. ...
![Ap Unit 6 Exam Questions Correctly Answered 2024.](/docpics/4940624/6611e89c0420f_4940624_121_171.jpeg)
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Ap Unit 6 Exam Questions Correctly Answered 2024.
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Ap Unit 6 Exam Questions Correctly Answered 2024. 
 
 
Scientists conducted a transformation experiment using E. coli bacteria and the pTru plasmid. Samples of the pTru plasmid (lane A) and the chromosomal DNA from two different E. coli strains that the scientists attempted to transform (lane B and lane C) were compared using gel electrophoresis. The results are shown in Figure 1. - CORRECT ANSWER 
 
Which of the following statements best explains the experimental results observed in Figure 1 ?...
![WGU D027 Practice Test Practice test for OA Questions and Answers 2023](/docpics/3471439/650b4010d1e2c_3471439_121_171.jpeg)
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WGU D027 Practice Test Practice test for OA Questions and Answers 2023
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A patient has endured several dosage adjustments of his tricyclic antidepressant, so 
the provider recommends genetic testing. Which statement correctly describes the 
rationale for genetic testing? - The CYP2D6 gene influences metabolism of 
tricyclic antidepressants and certain other drugs. 
According to the Centers for Disease Control and Prevention, the 10 most costly 
chronic conditions include cardiovascular diseases, obesity, asthma, diabetes, 
smoking and alcohol related conditions,...
![Internal Medicine EOR |281 questions| with correct answers](/docpics/63f2564b45e67_2387952.jpg)
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Internal Medicine EOR |281 questions| with correct answers
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What age do you being colon CA screening? CORRECT ANSWER begin at 50 
or if one family member has it then you begin at age 40 or 10 years before the age of onset in the family member 
 
Major of colorectal CAs are? CORRECT ANSWER adenocarcinomas 
 
most specific and sensitive dx test for colorectal cancer? CORRECT ANSWER Colonoscopy 
 
What can be used as a surveillance method for recurrence of colorectal cancer? CORRECT ANSWER CEA tumor marker 
 
Villous adenomas vs. tubular adenomas? CORRECT ...
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