clinical and food microbiology lecture 1-16

Aims of the clinical microbiology laboratory. • To provide accurate information about the presence or absence of microorganisms from a clinical specimen • To provide antimicrobial susceptibility information on the microorganism(s) recovered • Accurate diagnosis and sensitivity testing: (a...

LECTURE OVERVIEW • Normal flora of the URT • Primary and secondary bacterial invaders • Clinical manifestations, associated microorganisms and treatment options for common URTI • Streptococcus pyogenes (Group A Strep): virulence factors • Case study: laboratory diagnosis of streptococ...

LECTURE OVERVIEW. • Acute/ Chronic LRTI (focus on pneumonia) • Clinical manifestations, associated microorganisms and treatment of community acquired pneumonia (CAP) and hospital acquired pneumonia (HAP) • Streptococcus pneumoniae: virulence factors • Case study: pneumococcal pneumonia ...

LECTURE OVERVIEW. Mycobacteria Epidemiology of Tuberculosis Pathogenesis of pulmonary TB and clinical presentation Laboratory diagnosis Treatment of pulmonary TB: British Thoracic Society guidelines and NICE guidelines

• Definitions of UTI • Epidemiology of UTI • Micro-organisms (aetiological agents/pathogens) associated with UTI • Pathogenesis of UTI (host risk factors; virulence factors of E.coli (UPEC) • Treatment and prevention of UTI • UTI case study: diagnostic microbiology

LECTURE OVERVIEW. • STI background; current figures • Aetiological agents of STI • Overview of gonorrhoea, chlamydia, herpes, genital warts • Epidemiology, clinical manifestations, laboratory diagnosis, pathogenesis and treatment of gonorrhoea • Treatment / prevention of STI

• History of syphilis - 21st century syphilis • Epidemiology of 21st century syphilis • Treponema pallidum –physiology and virulence factors • Clinical manifestations of syphilis • Laboratory diagnosis (non culture techniques) • Treatment / prevention

• Define gastrointestinal infection • Clostridium difficile Associated Disease (CDAD) - Epidemiology; risk factors for CDAD - Pathogenesis / C. difficile ribotype 027 - Clinical manifestations of CDAD - Laboratory diagnosis (culture / non-culture) - Treatment and prevention

• Define sepsis • Understand the symptoms • Understand incidence, mortality and demographic of sepsis • Understand diagnostic methods • Be able to give examples of the different microorganisms that can cause sepsis • Describe approaches to treat sepsis

From this lecture you should understand What is antibiotic resistance How antibiotic resistance emerges Main mechanisms of antibiotic resistance and suitable examples of each Difference between adaptive and mutational resistance What is antibiotic resistance. • The ability of bacteria to...

To introduce food as a vehicle for foodborne disease. • Following this lecture, you should be able to: • Recognise the significance of food poisoning (FP) and foodborne disease (FBD). • Identify the variety of agents causing FP & FBD. • Understand the incidence of the major causative age...

– To highlight current & emerging foodborne pathogens using Salmonella Campylobacter and E. coli O157 as examples. – Following this lecture you should be able to: • Relate the microbiology, epidemiology and pathogenicity of Salmonella, Campylobacter & E. coli O157. • Define the symptoms p...

• Understand the difference in Phenotypic and Genotypic methods for epidemiological typing of pathogens. • Explain why sub-species typing is important in different scenarios. • Describe how to conduct and the reasoning for a number of phenotypic methods of typing such as: Serotyping, Phage...

• Aim – To study cleaning & disinfection practice in food hygiene and methods for assessing cleaning efficacy. • Objectives – Following this lecture you should be able to: • Explain the difference between cleaning & disinfection. • Define the terminology used in cleaning & disinfect...