Coagulation Modifiers Questions And Answers Graded A+

1. Prevent clot formation by inhibiting particular clotting factors 2. Prevent clot formation by interfering with platelet function 3. Lyse clots that have already formed 4. Promote the coagulation of blood 5. Reduce blood viscosity 6. Act as antagonists to the other medications - 1. Anticoagulants 2. Antiplatelets 3. Thrombolytics 4. Antifibrinolytics 5. Hemorheologics 6. Reversal drugs 1.________ inhibit platelet aggregation and formation of platelet plugs, which are helpful in preventing heart attacks and strokes. 2._____________ alter platelet function without interfering with normal platelet activity. 3._____________ are a classification of drugs that are used to break down clots or thrombi that have formed. 4.____________are hemostatic drugs that promote blood coagulation for conditions of excessive bleeding. - 1. Antiplatelet drugs 2. Hemorrhagic drugs 3. Thrombolytic drugs 4. Antifibrinolytic drugs A coagulation modifier drug whose mechanism of action is to promote coagulation of the blood is called a(n) ___________ and is used to _________. - antifibrinolytic, manage excessive bleeding Choose the correct word(s) from the drop-down list to complete the following statements regarding reversal drugs. - 1. Protamine Sulfate2. Warfarin 3. Idarucizumab 4. Rivaroxaban Coagulation modifier drugs is a class of medication that includes medications? - *Aspirin *Warfarin *Heparin Coagulation modifiers are a group of medications that 1.______________ clot formation as well as lysing a preformed clot and reversing the action of 2._______________. - 1. Both promote and prevent 2. Anticoagulant From the drop-down menu, select the term that best fits the definition. - 1. Coagulation 2. Fibrin 3. Fibrinolysis 4. Hemophilia 5. Hemostasis 6. Mechanical means of hemostasis 7. Surgical means of hemostasis 8. Pharmacologic means of hemostasis 9. Embolus 10. Thrombus Match the coagulation modifier drug's subclass to the correct medications. Note: Several of the subclasses have more than one medication listed as correct choices. - Anticoagulants -heparin -warfarin -enoxaparin -dabigatran etexilate-apixaban Antiplatelets -clopidogrel bisulfate -abciximab Thrombolytics -alteplase Antifibrinolytics -aminocaproic acid Hemorheologics -pentoxifylline Reversal drugs -protamine sulfate -phytonadione -idarucizumab -coagulation factor Xa (recombinant) The coagulation cascade system is triggered by 1.____________, which then triggers 2.___________________ pathway of intricate steps, each step triggering the next when 3.___________ are/is activated. The ultimate result of this system is a large concentration of 4._____________. - 1. An injury to a blood vessel 2. Either an intrinsic or an extrinsic 3. Clotting factors 4. FibrinThe coagulation modifier drugs are broken down into several subclasses or categories based on their hemostasis reversal or promotion action. Which items are mechanisms of action for this class of drug? Select all that apply. - *Thrombus prevention *Thrombus promotion *Lysing of a preformed thrombus *Anticoagulation reversal The reverse of the coagulation process is the 1.____________ system. Fibrinolysis is the 2.___________ of thrombi. This is an important part of hemostasis in order to prevent excessive coagulation, blocked blood vessels, or mobilized thrombi called 3.___________. - 1. Fibrinolytic 2. Breakdown 3. an embolus Warfarin is an 1.___________ medication whose mechanism of action is to 2.____________ clot formation by inhibiting particular clotting factors. - 1. Anticoagulant 2. Prevent What is another term for anticoagulant? - Antithrombotics What is another term for antifibrinolytics? - Hemostatics Which of these medications is a coagulation modifier whose subclass is a reversal drug? Select all that apply. - *Protamine sulfate *Vitamin K Which one of these coagulation modifier drugs has a mechanism of action that is to lyse a thrombus that has already formed? Match it to its subclass. - Medication -Alteplase Subclass -Thrombolytic