NAPLEX Diabetes
test used to identify patients who still produce insulin - ANS C peptide
examples of macrovascular disease - ANS coronary artery disease, cerebrovascular disease,
peripheral artery disease
which group has a higher risk of DM with a lower BMI - ANS Asian Americans
Pre diabetes dx criteria - ANS fasting glucose 100-125; 2 hour plasma glucose (75g) 140-199;
or A1c 5.7-6.4%
Diabetes criteria for diagnosis - ANS symptoms plus random glucose > 200; fasting > 126; 2
hour OGTT > 200 or A1c > 6.5%
meds that can increase blood glucose - ANS atypical anti psych, azoles (posa), beta agonists,
BB (carvedilol, propranolol), cough syrup, cyclosporine, FK, sirolimus, Diazoxide, interferon alfa,
niacin, octreotide, protease inhib, quinolones, steroids, thiazides, loops
drugs that lower blood glucose - ANS linezolid, lorcaserin (Belviq), Octreotide (with Type 1),
pentamidine, propranolol and non-selective BB, Quinine, quinolones
Gestational diabetes goals - ANS preprandial < 95; 1 hour post < 140, 2 hours post < 120
Pregestational diabetes goals - ANS A1c < 6%, preprandial 60-99, peak postprandial 100-129
goal waist circumference - ANS < 35 inches female; < 40 inches male
goal fiber intake - ANS 14 grams per 1,000 kcal; 25 g for females and 38 g for males
who should get aspirin therapy as primary prevention - ANS males > 50 and females > 60 with
at least 1 additional factor (HTN, CVD, family hx, smoking, etc)
what should be used if patient has aspirin allergy - ANS clopidogrel 75mg
benefit of ACEI and ARBs - ANS delay progression to diabetic nephropathy in those with
albuminuria
when do patients qualify for high intensity statin - ANS <40 years with overt CVD or >40 year
with CVD risk factors or overt CVD
, vaccinations indicated for diabetic patients - ANS Hep B if unvaccinated between 19-59;
influenza, pneumococcal; Tetanus if due
ADA guidelines - ANS < 7%, preprandial 80-130; peak postprandial < 180
AACE guidelines - ANS < 6.5%, preprandial < 110, peak postprandial < 140
when should initial therapy contain two drugs - ANS A1c >/= 9
when should initial therapy include insulin - ANS A1c > 10 or BG > 300
at one point should an additional agent be added - ANS A1c not at goal after 3 months
which three drug regimens are not recommended - ANS metformin + DPP4 + GLP1 or
metformin + SGLT2 + GLP1
medications with only moderate efficacy - ANS DPP4 inhib, SGLT2 inhib, pramlintide
moderate risk of hypoglycemia - ANS SUN and meglitinides
drugs that can cause weight loss - ANS GLP1 agonists, SGLT2 inhib, pramlintide
drugs that cause weight gain - ANS insulin, SUs, meglitinides, TZDs
which medications increase insulin secretion - ANS SUs and Meglitinides
how does metformin work - ANS decreases hepatic glucose production, decreases glucose
absorption, and increases sensitivity
when is metformin CI - ANS Scr > 1.5 in males, > 1.4 in females
Metaglip - ANS metformin and glipizide
Glucovance - ANS metformin and glyburide
Actoplus Met - ANS pioglitazone and metformin
Avandamet - ANS rosiglitazone and metformin
Janumet - ANS sitagliptin and metformin
Kombiglyze - ANS saxagliptin and metformin
test used to identify patients who still produce insulin - ANS C peptide
examples of macrovascular disease - ANS coronary artery disease, cerebrovascular disease,
peripheral artery disease
which group has a higher risk of DM with a lower BMI - ANS Asian Americans
Pre diabetes dx criteria - ANS fasting glucose 100-125; 2 hour plasma glucose (75g) 140-199;
or A1c 5.7-6.4%
Diabetes criteria for diagnosis - ANS symptoms plus random glucose > 200; fasting > 126; 2
hour OGTT > 200 or A1c > 6.5%
meds that can increase blood glucose - ANS atypical anti psych, azoles (posa), beta agonists,
BB (carvedilol, propranolol), cough syrup, cyclosporine, FK, sirolimus, Diazoxide, interferon alfa,
niacin, octreotide, protease inhib, quinolones, steroids, thiazides, loops
drugs that lower blood glucose - ANS linezolid, lorcaserin (Belviq), Octreotide (with Type 1),
pentamidine, propranolol and non-selective BB, Quinine, quinolones
Gestational diabetes goals - ANS preprandial < 95; 1 hour post < 140, 2 hours post < 120
Pregestational diabetes goals - ANS A1c < 6%, preprandial 60-99, peak postprandial 100-129
goal waist circumference - ANS < 35 inches female; < 40 inches male
goal fiber intake - ANS 14 grams per 1,000 kcal; 25 g for females and 38 g for males
who should get aspirin therapy as primary prevention - ANS males > 50 and females > 60 with
at least 1 additional factor (HTN, CVD, family hx, smoking, etc)
what should be used if patient has aspirin allergy - ANS clopidogrel 75mg
benefit of ACEI and ARBs - ANS delay progression to diabetic nephropathy in those with
albuminuria
when do patients qualify for high intensity statin - ANS <40 years with overt CVD or >40 year
with CVD risk factors or overt CVD
, vaccinations indicated for diabetic patients - ANS Hep B if unvaccinated between 19-59;
influenza, pneumococcal; Tetanus if due
ADA guidelines - ANS < 7%, preprandial 80-130; peak postprandial < 180
AACE guidelines - ANS < 6.5%, preprandial < 110, peak postprandial < 140
when should initial therapy contain two drugs - ANS A1c >/= 9
when should initial therapy include insulin - ANS A1c > 10 or BG > 300
at one point should an additional agent be added - ANS A1c not at goal after 3 months
which three drug regimens are not recommended - ANS metformin + DPP4 + GLP1 or
metformin + SGLT2 + GLP1
medications with only moderate efficacy - ANS DPP4 inhib, SGLT2 inhib, pramlintide
moderate risk of hypoglycemia - ANS SUN and meglitinides
drugs that can cause weight loss - ANS GLP1 agonists, SGLT2 inhib, pramlintide
drugs that cause weight gain - ANS insulin, SUs, meglitinides, TZDs
which medications increase insulin secretion - ANS SUs and Meglitinides
how does metformin work - ANS decreases hepatic glucose production, decreases glucose
absorption, and increases sensitivity
when is metformin CI - ANS Scr > 1.5 in males, > 1.4 in females
Metaglip - ANS metformin and glipizide
Glucovance - ANS metformin and glyburide
Actoplus Met - ANS pioglitazone and metformin
Avandamet - ANS rosiglitazone and metformin
Janumet - ANS sitagliptin and metformin
Kombiglyze - ANS saxagliptin and metformin
