All humans suffer from hypoascorbemia? (T/F) correct answer: True
Which enzymes require folate as a co-substrate? correct answer: Methionine synthetase, MTFR, SHMT
Which mineral is an essential factor in the action of glutathione peroxidase (GPX) in the reduction of organic peroxides and hy...
Metabolic Spring Test 2| 204 questions| with
complete solutions
All humans suffer from hypoascorbemia? (T/F) correct answer:
True
Which enzymes require folate as a co-substrate? correct answer:
Methionine synthetase, MTFR, SHMT
Which mineral is an essential factor in the action of glutathione
peroxidase (GPX) in the reduction of organic peroxides and
hydrogen peroxide? correct answer: Selenium
What is a genetic disorder that ultimately results in the excessive
accumulation of iron in certain tissues. This disorder affects all
iron-requiring enzyme reactions as well correct answer:
Hemochromatosis
Which mineral participates in all aspects of energy metabolism
including glycolysis, beta-oxidation and the TCA cycle? correct
answer: Magnesium
What enzymes require thiamine, in the form of TPP for full
activity? correct answer: BCKD complex, PDH complex, and
alpha KG complex
A riboflavin deficiency would affect the ETC (T/F) correct
answer: True
,What are the required cofactors in the ETC? correct answer:
Copper, iron, and zinc
Riboflavin co-enzymes remain bound to their enzymes during
the oxidation-reduction reactions they participate in. The
complexes are called correct answer: Flavoproteins
Why does thiamin utilization increase in cancer patients? correct
answer: Thiamin is necessary in the Pentose Phosphate
Pathway, which is up-regulated in cancer
Thiamine is important to fatty acid synthesis due to its
requirement as what co-enzyme for the hexose monophosphate
shunt (pentose phosphate pathway)? correct answer:
transketolase
Phosphate induces a conformational change in the pyruvate
kinase enzyme (T/F) correct answer: False-- potassium does
Which mineral acts as a chelating agent for ATP (i.e. binds it)?
correct answer: Magnesium
Which vitamins are required for the fatty acid oxidation (beta-
oxidation) pathway? correct answer: Pantothenic acid,
riboflavin, and niacin
Mild niacin deficiency can cause an intolerance to cold (T/F)
correct answer: True
The ETC requires NADPH (T/F) correct answer: False
, What is the purpose of antioxidant production? correct answer:
Balancing free radicals
In glycolysis what enzyme serves as a bridge between the
enzyme and ATP? correct answer: Magnesium
In the paper you read on Scholar, what were the findings related
to Vitamin D and obesity? correct answer: Supplementation
with Vitamin D lead to increased fat mass loss in subjects
What does fatty acid entry into the cell require? correct answer:
Pantothenic acid
What does carnitine synthesis require? correct answer: vitamins
C, B6, niacin, and iron
What is formed during beta-oxidation of fatty acids? correct
answer: Acteyl-CoA, FADH2, NADH
What vitamin transcriptionally regulates the genes involved in
beta-oxidation? correct answer: Vitamin D
One sign of B6 deficiency is Pellagra like symptoms (T/F)
correct answer: True
Can folate supplementation prevent NTD in shmt1KO? correct
answer: Folate only (not chlorine)
What might be the consequence of an SHMT2 KO? correct
answer: Reduced one-carbon metabolism-renal tube defects and
anemia
Voordelen van het kopen van samenvattingen bij Stuvia op een rij:
Verzekerd van kwaliteit door reviews
Stuvia-klanten hebben meer dan 700.000 samenvattingen beoordeeld. Zo weet je zeker dat je de beste documenten koopt!
Snel en makkelijk kopen
Je betaalt supersnel en eenmalig met iDeal, creditcard of Stuvia-tegoed voor de samenvatting. Zonder lidmaatschap.
Focus op de essentie
Samenvattingen worden geschreven voor en door anderen. Daarom zijn de samenvattingen altijd betrouwbaar en actueel. Zo kom je snel tot de kern!
Veelgestelde vragen
Wat krijg ik als ik dit document koop?
Je krijgt een PDF, die direct beschikbaar is na je aankoop. Het gekochte document is altijd, overal en oneindig toegankelijk via je profiel.
Tevredenheidsgarantie: hoe werkt dat?
Onze tevredenheidsgarantie zorgt ervoor dat je altijd een studiedocument vindt dat goed bij je past. Je vult een formulier in en onze klantenservice regelt de rest.
Van wie koop ik deze samenvatting?
Stuvia is een marktplaats, je koop dit document dus niet van ons, maar van verkoper Demetrius. Stuvia faciliteert de betaling aan de verkoper.
Zit ik meteen vast aan een abonnement?
Nee, je koopt alleen deze samenvatting voor €12,25. Je zit daarna nergens aan vast.