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Summary Glossary and formulas HNH-24806

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Begrippenlijst met bijbehorende formules voor het vak Introduction to Epidemiology and Public Health HNH-24806 Wageningen Universiteit.

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  • 22 september 2020
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Introduction to Epidemiology and Public Health - glossary
HNE-24806

Glossary


Absolute risk reduction (ARR) = attributable risk (AR) = risk difference

Analytical epidemiology: study of causes of a disease; exposure-disease associations

Antagonism: combination of exposures “silences” the separate effects

Attack rate: amount of people who did something before they got sick

Attributable fraction (AF): Tells the proportion of disease in those exposed that can be attributed to the exposure

Attributable risk: measures the actual amount of disease that can be attributed to a particular exposure

Caplan’s prevention model: primary, secondary and tertiary prevention

Case control study: retrospective: back in time
→ define population → see if they are diseased or not → see if people were exposed or not → find associations

Case-fatality ratio (CFR): proportion of people with a given disease or condition who die from it in a given period

Cluster: aggregation of relatively uncommon diseases in space and/or in time in amounts that are believed or
perceived to be greater than could be expected by chance

Cohort study: prospective: forward in time: longitudinal
→ define population → see if people are exposed or not → see if they get diseased or not → find associations between
exposure and disease

Collective prevention: state responsibility and a government task in terms of policy, organisation and funding

Community trials: preventive trials in which the intervention is implemented at the community level and are generally
conducted when it would be impossible to offer the intervention at the individual level

Comparative mortality figure (CMF): compares age-adjusted mortality rates of two countries
→ derived from direct standardisation

Component cause: factor that contributes to the disease, but cannot cause it on its own

Confidence interval: information about the accuracy of your mean/difference/median/estimator

Confounding: biased exposure or outcome relation resulting from lack of comparability exposed and unexposed group

Consort statement: rules to adhere to if you want to publish your trial; e.g. it’s obligatory to include a flow chart

Continuous outcome: follow level of the outcome in time, e.g. change in blood pressure during treatment

Cross-sectional study: gather data on exposure and disease simultaneously and see if there are associations
→ all variables are measured at the same moment in time

Crude rates: describe over all incidence or death rate in a population without taking any other features of the
population into account

Cumulative incidence (CI): incidence proportion; measures amount of people who develop the disease during a
1-8

, specified period
= incidence proportion
≈ distance travelled by a car during a specified interval of time 60 km in one hour
Descriptive epidemiology: amount/frequency of disease or other conditions in a population
Per person, place and time

Dichotomous outcome: occurrent in time of a disease or condition, e.g. hip fracture yes/no

Differential: association biased

Direct standardisation calculate the overall rate that you would see in a ‘standard’ population if it had the same age-
specific rates of disease as your study population

Disability-adjusted life years (DALY): measure of the burden of a disease or risk factor on a population. Sum of years
lost due to death before life expectancy + years lost due to disability
→ about disease; smaller = better

Disability-free life expectancy: number of years of life an individual of a given age is expected to live free of disability,
based on current morbidity and mortality rates

DISH:
 Determinants of diet and lifestyle epidemiology in public health
 Intake of food and nutrients “
 Status and function of the body epidemiology in academic setting
 Health and disease risk “

Double-blind: both participant and investigators don’t know who’s exposed

Ecological fallacy: ascribing characteristics to members of a group that they might not possess as individuals
e.g.: by studying the population, you are not sure if all stomach cancer patients are infected by H. pylori

Endemic: constant presence of a disease or infectious agent within a given geographic area or population group

Epidemiology: study upon people; measuring health, identifying the cause of ill-health and intervening to improve
health

Etiology: study of causes/origins of disease

Expected years of life lost (EYLL): number of years expected life lost due to a death at a given age; equal to the life
expectancy at that age

External validity: does the same thing happen in other settings/people/labs?

Good clinical practice (GCP): an international and scientific quality standard for designing, conducting, recording and
reporting trials in human subjects

Gordon’s prevention model: universal, selective, indicated and care-related prevention

Health adjusted life expectancy (HALE): taking into account the quality of life
→ calculated by using a life table

High risk strategy: e.g. try to move high risk individuals to the ‘normal BMI’ category (large shift)

Incidence proportion (IP): measures amount of people who develop the disease during a specified period
= cumulative incidence

Incidence rate (IR): rate at which new cases of a disease have occurred
≈ average speed of a car at a particular point in time 60 km/hour

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