Rtks Samenvattingen, Aantekeningen en Examens

when cells respond to an extracellular signal, they most often convert the information carried by this molecule from one form to another. What is this process called? - Answer-signal transduction When does signal transduction begin? - Answer-when the receptor on a target cell recieves and incoming extracellular signal and then produces intracellular signaling molecules that alter cell behavior extracellular signal molecules, released locally example: inflammation regulation at site of infe...

Final Exam: BIO1201/ BIO 1201 Review (Latest 2024/ 2025 Update) | Questions and Verified Answers| 100% Correct| Grade A – LSU Q: ligand: Signal molecule that binds to the receptor Q: three main types of membrane receptors Answer: -G protein-coupled receptors -Receptor tyrosine kinases -Ion channel receptors Q: G protein-coupled receptors (GPCRs) Answer: cell-surface transmembrane receptors that work with the help of a G protein Q: Receptor Tyrosine Kina...

Which of the following signaling types occurs during periods of development specifically for the secretion of growth factors? paracrine signaling Explain why a steroid hormone would require a carrier protein to transport it through the bloodstream. Steroid hormones are hydrophobic so they would need a carrier protein to carry it through the blood because carriers are hydrophilic Explain what a ligand is and give an example of one. A ligand is a molecule that has specificity for a given rece...

Biol 1201 Final – Gregg Latest Update Graded A+ local signaling animal cells may communicate by direct contact, or cell-cell recognition (paracrine and synaptic signaling) cell junctions Animal and plant cells; directly connect the cytoplasm of adjacent cells paracrine signaling the target cells lie near the secreting cells synaptic signaling a nerve cell releases neurotransmitter molecules into a synapse, stimulating the target cell endocrine (hormonal) signaling Specializ...

CPPS 325 FINAL EXAM WITH 100% CORRECT ANSWERS 2023/2024 Graded A+. What are the 5 well-known enzyme-linked cell surface receptors? - Correct Answer-1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific...

CPPS EXAM PRACTICE QUESTIONS WITH CORRECT ANSWERS 2023/2024 (Graded). What isSH1 domain characterized by? - Correct Answer-Catalytic domain of a protein, for example the receptor. and it has the kinase activity. It is responsible for phosphorylating tyrosine residues. What is SH2 domain characterized by? - Correct Answer-Binds peptides with consensus (positional information on C-terminal side of the phosphorylated tyrosine). Very specific. Mediates protein-protein interactions in cellular ...

CPPS 325 FINAL EXAM QUESTIONS WITH CORRECT ANSWERS 2023/2024 Graded A+. What is the only example of conformational change activation? - Correct Answer-Insulin receptor kinase. All other RTKs are activated through forms of dimerization. What are the two forms of dimerization? - Correct Answer-i) Receptors exist as unactivated dimers until ligand binds (Twist theory) ii) exist as monomers that are brought together and activated by ligand binding. What is the most common method of dimerizatio...

Units 1-5 - Memorize all 20 amino acids - Memorize what all the complex carbs look like and a few facts about them - Know Michaleis-Menton graph and be able to identify type of enzyme inhibitor - Be able to explain how to get Vmax and Km from Lineweaver-Burk - Know how to translate DNA to mRNA and know the peptide that would be translated o do not need to memorize codons - Outline steps of translation - Know about all categories of: o Lipids o Active/passive transport o Plasmids o Re...

What are the 5 well-known enzyme-linked cell surface receptors? - 1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific Serine/Threonine residues on IC signalling molecules How are RTK and TK Ass...

Lipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 1. mass greater than 500 Da 2. highly lipophilic - logP > 5 3. more than 5 hydrogen bond donors 4. more than 10 hydrogen bond acceptors Partition coefficient - ANSWER-p = C(octanol)/C(water) - ratio of the equilibrium concentrations of dissolved substance in a two-phase system containing two largely immiscible solvents (water & octanol) - Log10(P) Improved Lipinski Parameters - ANSWER-1. Partition...