CNPR Exam With Correct Answers

CNPR Exam 1. How are drugs sorted into therapeutic groups and classes? - ANS first by the conditions that they are used to treat. and then by their mechanisms of action 2. Bone marrow transplants. - ANS are a type of stem cell therapy. unless patient's own cells are reinjected. 3. What does AMA stand for? - ANS American Medical Association 4. What section of a drug's package insert describes situations in which the drug should not be used because the risks outweigh the therapeutic benefits? - ANS contraindications 5 What is tertiary care? - ANS highly specialized medical and surgical care provided by a large medical center for unusual or complex medical problems 6. Which of the following is NOT one of the stages in the classic approach to brand development strategy covered in your manual? - ANS brand quality 7 What are vasodilators used to do? - ANS decrease vascular resistance and increase blood flow 8. What is the name of the condition that occurs after a specific dose of a drug is given at such regular intervals that absorption and elimination (and therefore drug plasma concentration) have become fairly constant? - ANS Steady State 9. Which statement is TRUE about ocular administration? - ANS Ocular administration is used primarily to treat the eye. 10. Which entities invest's the most money in pharmaceutical R&D? - ANS U.S. pharmaceutical companies 11. How are most drugs excreted? - ANS via the kidneys 12. Over the last few decades, what has happened to legal limitations on sales' reps discussions about off label uses? - ANS Limitations have decreased. 14. What does it mean if two drugs are at parity? - ANS Both drugs are essentially in a neutral position. 15 Who is most likely to benefit from electronic sampling programs? - ANS Everyone would benefit equally from electronic sampling programs 16. When referring to medication dosage, which abbreviation means "one-half' - ANS SS 17 What is an internist? - ANS a physician who practices internal medicine 18. Which of the following is a type of white blood cell? - ANS Lymphocytes 19. Why are novice sales representatives often placed in charge of negotiating MCO formularies? - ANS They are not. This job is usually reserved for more experienced reps. 20. What distinguishes pharmacodynamics from pharmacokinetics? - ANS Pharmacodynamics studies the how the body affects drugs. 21 What proportion of the drugs tested on human subjects are eventually approved by the FDA? - ANS about 70% 22. According to a study discussed in your manual, how do most physicians prefer to receive their drug samples? - ANS directly from sales representatives 23. Which of the following is an example of a central value? - ANS I buy Advil to show that I'm a modern consumer. 24. Which of the following specialties likely has the MOST emergency calls? - ANS cardiologist 25. What affects the rate of active transport? - ANS neither the availability of carriers nor the availability of energy 26. Over the last few decades, what has happened to the FDA approval time for new drugs? - ANS It has been shortened to reduce the cost of new drug development. 27. Which of the following would NOT help improve compliance? - ANS pharmacists understanding how generics differ from brand name drugs 28. Which entity chooses a drug's trade name? - ANS the FDA 29. What type of stem cells are obtained from embryos and can develop into any cell type? - ANS totipotent 30. As the price a patient pays for a prescription increases, what happens to the likelihood that the patient will fill it? - ANS It remains unaffected because the prescription is needed 31. Most involuntary movements come from which type of muscle tissue? - ANS cardiac and smooth 32. Which of the following is NOT one of the body's major organ systems? - ANS the cellular system 33. How do most drugs exert their primary physiological effects? - ANS by binding to cell receptors that are sensitive to their presence 34. What is the most reliable source of information for determining therapeutically equivalent drug products? - ANS Orange Book 35. What does subcutaneous mean? - ANS beneath the outer skin 36. What should a sales representative do if all of the prime spaces in a drug cabinet are coccupied? - ANS ask staff for permission to move some of the other products in the cabinet 37. It is inappropriate for physicians' prescribing behaviors to be educated by their personal tastes and idiosyncrasies - ANS TRUE 38.The FDA defines API as the active__ ingredient in a drug, which produces the desired change in the body. - ANS pharmaceutical 39. What are the 2 legal classifications of wholesalers? - ANS primary and secondary wholesale distributors 40.What term describes the usage of a medication for purposes other than the FDA-approved indications on the labeling? - ANS off-label usage 41. What is the acronym for pharmacokinetics? - ANS PK 42. The dosage range of a drug that is both safe and beneficial is known as the therapeutic window. - ANS True 43. What is typically NOT a characteristic of a pharmaceutical sales rep? - ANS Pharmaceutical sales reps are not concerned about competitors. 44. What entity grants drug patents? - ANS The US Patent and Trademark Office 45. Which of the following refers to all active and inert pharmaceutical ingredients in a drug,including fillers and colors? - ANS formulation 46. What is the difference between potency and efficacy? - ANS potency refers to the drug's strength, while efficacy refers to its effectiveness 47. What is the minimum level of education required for a nurse practitioner? - ANS a graduate degree 48. How many names must a drug have? - ANS at least three 49. How has a longer development time increased the cost of bringing a new drug to market? - ANS Increasing the cost of capital 50. Senior citizens consume over times as many pharmaceuticals as people under 65. - ANS three 51. What agency regulates the distribution and use of narcotics? - ANS DEA 52. What is passive diffusion? - ANS when a substance freely moves through a membrane from a high concentration gradient to a low one 53. What are the MAIN categories of drugs under FDA jurisdiction? - ANS prescription and non prescription 55. What are all metabolites? - ANS products of metabolism 56. When a drug is administered orally, where does first-pass metabolism occur? - ANS liver 57. What is the medical term for swelling? - ANS edema 58. Which of the following is NOT part of the Seven Step Cascade of Emotion? - ANS be a consultant, not a rep 59. Which part of a clinical research paper is frequently referred to as the road map? - ANS abstract 60. Which of the following is a main active ingredient in lung surfactants? - ANS theophylline 61. What does parenteral mean? - ANS injection 62. Which term denotes a type of substance that enhances the action of a drug or antigen? - ANS adjunvant 63. If a sales representative's product is placed on the second tier of a standard three-tier formulary, which of the following is most likely true? - ANS It probably has exclusive preferred status if it is not at parity with any other drugs 64. Which of the following is NOT one of the four basic transport mechanisms? - ANS homeostasis 65. Which statement accurately describes a relationship between drug agonists and antagonists? - ANS Agonists and antagonists can be used together. 66. What is the study of the effects and movement of drugs in the human body? - ANS clinical pharmacology 67. According to your manual, what is a common complaint that physicians have about traditional sampling methods? - ANS that drug sample supply is too unpredictable 68. Which of these entities is formed by two or more hospitals or other healthcare entities to negotiate reduced rates with its aggregated purchasing power? - ANS GPO 69. What is another name for a drug derived from a biologic compound? - ANS large molecule 70. What is the most common policy regarding pharmaceutical reps dispensing drug samples in hospitals? - ANS drug sampling is often forbidden 71 Which of the following would help you build trust with a physician? - ANS asking if he or she is having any problems with the managed care coverage of your products 72. What term denotes the difference between the usual effective dose and the dose that induces severe or life-threatening side effects? - ANS margin of safety 73. What are excipients? - ANS the inert ingredients in a drug formulation 74. What is another term for the AWP? - ANS list price 75. Which of these is the most likely use for a uterotonic agent? - ANS to induce labor 76. As of November 2013, which of these countries has legalized DTC advertising of prescription drugs? - ANS none of these 77. Why are oral drugs often taken on an empty stomach? - ANS to pass through the stomach more quickly 78. What is one factor that differentiates community health centers from hospitals? - ANS community health center formularies are more restrictive 79. How does drug sampling provide a social benefit? - ANS doctors often use drug samples to treat patients who otherwise could not afford it 80. Which medical term denotes the use of a stethoscope to listen to the heart? - ANS ausculation 81. What do enteric coatings do? - ANS prevents dissolution in the stomach 82. What is the duration of exclusivity for orphan drugs? - ANS 7 years 83. What do National Account Managers do? - ANS negotiate contracts with MCO and PBM 84. What does it usually mean if a drug recall is voluntary? - ANS The manufacturer has recalled the product on its own. but negotiated with the FDA beforehand. 85. Which phase of clinical trials is also known as the pivotal phase? - ANS Phase III 86. During which phase of clinical trials is the new drug's safety and effectiveness first tested in the target group? - ANS Phase II 87. How do antacids work? - ANS by raising gastric PH 88. What is one of the biggest time wasters for a pharmaceutical sales rep? - ANS Travel Time 89. What happens when equilibrium is reached? - ANS equal numbers of molecules cross the membrane in both directions 90. What are the most common vectors used in gene therapy? - ANS viruses 91. What is the percentage fee that the dispenser pays the wholesaler for distribution? - ANS upcharge 92. What is the difference between a chronic (or continuing) reaction, and a delayed reaction? - ANS chronic reactions persist for a long time, delayed reactions take some time to develop 93 What is clinical effect? - ANS the response produced by a medication 94. Which of the following is an example of noncompliance? - ANS a patient forgetting to take a drug at a specified time of day 95. What is the average circulation time of blood? - ANS about a minute 96. What is one way in which pharmaceutical selling is different from selling in most other industries? - ANS representative do NOT sell to the end user of the product 97. From what types of entities do primary wholesale distributors buy most of their drugs? - ANS manufacturers 98.What is the Office of the Inspector General (01G)? - ANS an arm of the Dept of Health and Human Services 99. What are doctors required to consider when deciding whether or not to prescribe a particular drug? - ANS the severity of the disorder being treated and the effect it has on the patients quality of life 100. Which entity assigns a new drug its generic names? - ANS the United States Adopted Name Council 101. Drugs can be used days beyond their expiration date. - ANS drugs never can be used beyond expiration date 102. What is necessary for a drug to be excreted extensively via the kidneys? - ANS The drug must be water-soluble, and not bind too tightly to protein in the bloodstream 103. Which organization or individual initiates the clinical trial and finances the study? - ANS sponsor 104. The name describes the atomic or molecular structure of a drug. - ANS chemical 105. Under PhRMA Code, is it acceptable or unacceptable for a pharmaceutical sales rep to take a physician and the physician's spouse to a fundraising dinner? - ANS never (unacceptable) 106. The Hatch-Waxman Act is considered the most significant drug-related affecting the pharmaceutical industry since 1962. - ANS legislation 107. What term denotes the the extent, quality, or degree to which a substance is poisonous or harmful to the body? - ANS toxicity 108. What issue has MOST encouraged consumers' desire to see more OTC medications? - ANS lack of insurance coverage 109. What is the degree to which a medication produces a therapeutic effect? - ANS efficacy 110. What is the most important benefit of electronic prescribing? - ANS safety 111. When does the FDA regulate generic drugs? - ANS always 112. Which phase of trials largely determines the clinical dose? - ANS Phase II trials 113. What is an advantage of inactivated vaccines over attenuated vaccines? - ANS inactive vaccines have a more stable shelf life 114. Which medical term denotes a low supply of oxygen due to low blood flow? - ANS ischemia 115. What are the two main types of prescription drug marketing? - ANS professional physician promotions and direct-to-consumer advertising 116. What is the site of delivery for subcutaneous injections? - ANS fatty tissue beneath the surface of the skin 117. What must be contained in the Description section of a pharmaceutical package insert? - ANS the proprietary name and the established name 118. What is the study of a medication's effects as it travels through the body? - ANS pharmacokinetics 119. Customers purchase products from people they like, trust, and respect. This is called the - ANS likeability factor 120. What is penicillin's primary mechanism of action? - ANS it disturbs bacterial cell wall synthesis 121. According to your manual, how has the U.S. healthcare marketplace changed in the last few decades? - ANS managed care has been increasingly replaced by more patient centered approaches 122. How does pharmaceutical marketing help narrow the treatment gap? - ANS it encourages patients to take more active roles in their healthcare 123. What do immunosuppressive agents do? - ANS reduce risk of rejection of foreign bodies 124. What types of drugs are EGFR inhibitors? - ANS antineoplastics 125. Which of the following means outside of the living body? - ANS ex vivo 126. The FDA requirements for nutraceuticals and medicinal herbs are just as stringent as for pharmaceuticals. - ANS False 127. What is the estimated net gain of private-sector healthcare's contributions to increased U.S. life expectancy? - ANS 2-5 trillion 128. Which statement is TRUE regarding post-approval drug monitoring? - ANS the FDA can choose to withdraw their approval if new evidence arises 129. Which term denotes when tolerance to one medication causes increased tolerance to another medication? - ANS cross tolerance 130. Patents expire __ years from the date of filing. - ANS twenty 131. After a trade-name drug's patent expires, how may generic versions of it be sold? - ANS only under the branded generic name 132. What is required for a new pharmaceutical to be considered a viable therapy? - ANS it is more effective, causes fewer serious adverse effects than other drugs on the market 133. Under the AMA guidelines, who is ultimately responsible for minimizing conflicts of interest? - ANS doctors 134. The act of dispensing a pharmaceutical alternative for the product prescribed is - ANS pharmaceutical substitution 135. What does it mean if a drug is said to have a wide margin of safety? - ANS there is a lower chance of severe or life threatening side effects 136. Which of the following is the correct medical acronym for effective dose? - ANS ED 137. Why is one group of subjects given an active drug, while another group only receives a placebo? - ANS to assess the drugs effectiveness 138. A generic version is likely to have some inactive ingredients that are different from those of the original drug. - ANS True 139. Which of the following is an example of a functional value? - ANS I drink coco cola because I like the taste 140. Where are most drugs metabolized? - ANS liver 141. What is essential to the ethical requirement that subjects be selected fairly? - ANS subjects should be selected based on scientific objectives 142. Which of the following is the most appropriate salutation for a cover letter if you cannot find a contact name? - ANS Dear Sir or Madam 143. What is part of becoming an indispensable pharmaceutical sales rep? - ANS asking for feedback 144. Which of the following is NOT typically included in the indications and usage section of the package insert information? - ANS the drugs active metabolites 145. Which term denotes the practice of classifying physicians and other potential prescribers by anticipated prescription volume? - ANS deciling 146. What makes a drug eligible for fast track approval from the FDA? - ANS it treats patients with a serious life-threatening condition 147. In the gastrointestinal tract, help break up tablets to ensure full release of the active pharmaceutical ingredient. - ANS disintegrants 148. According to your manual, what does the PDRP do? - ANS it limits sales reps abilities to see individual physicians prescribing data 149. What are the components of the central nervous system? - ANS the brain and spinal cord 150. Which term denotes the origin or cause of a medical condition? - ANS etiology 151. Patients diagnosed with Type 1 diabetes - ANS have an autoimmune disease 152. Which DTC pharmaceutical marketing tactic is permitted in European countries? - ANS disease state ads 153. What is one way in which psychologists DIFFER from psychiatrists? - ANS psycologist deal with emotional than physical issues 154. What are PBMs? - ANS organizations that negotiate between pharmaceutical companies and large drug purchasers 155. How does the Hatch-Waxman Act protect research-based drug manufacturers? - ANS by providing a 30 month cooling off period 156. What is the process of adjusting drug doses to achieve the maximum positive therapeutic effects while minimizing adverse or side effects? - ANS titration 157. Which of the following is studied more in pharmacodynamics than in pharmacokinetics? - ANS the transportation of the drug to the specific site for drug receptor interactions 158. How does the healthy human immune system use MHC markers? - ANS substances without MHC markers are discerned as foreign and targeted for destruction 159. What is a behind-the-counter drug? - ANS an OTC drug that must be closely monitored by the pharmacist 160. When do MSLs meet with clinicians? - ANS at nearly any stage of the products life cycle