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Class notes PHARMACOLOGY Essentials of Medical Pharmacology, ISBN: 9789352704996 R141,99
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Class notes

Class notes PHARMACOLOGY Essentials of Medical Pharmacology, ISBN: 9789352704996

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Notes are important for the competitive exams after pharmacy. Contains classification of drug with basics. kindly refer and review So I will improve.

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  • September 23, 2021
  • 28
  • 2020/2021
  • Class notes
  • Dr. sameer sawant
  • All classes
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Antiadrenergic Drugs
• Adrenergic Receptor Antagonists
• Sympatholytics




1

,Introduction
 Drugs used to block the actions of endogenous
catecholamine (NA and Adr)
 Great clinical value
 They occupy adrenergic receptors (alpha and beta)
but do not produce signal transduction – Affinity is
there but without intrinsic activity
 Clinically 2 (two) distinct groups – alpha blockers
and beta blockers



2

, Contd.
 In clinical therapeutics, nonselective antagonists have
been used in the treatment of pheochromocytoma
(adrenal tumors that secrete catecholamines)
 Alpha-1 selective antagonists are used in primary
hypertension and benign prostatic hyperplasia
(BPH)
 Beta-receptor antagonist - hypertension, ischemic
heart disease, arrhythmias, endocrinologic and
neurologic disorders, and other conditions
 Blockade of central nervous system dopamine receptors
is very important – Antiemetic, Antipsychotic and
tricyclic anti-depressants


pheochromocytoma




3

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