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Summary Pharmacology: The Autonomic, Somatic and Sensory Nervous System R60,00   Add to cart

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Summary Pharmacology: The Autonomic, Somatic and Sensory Nervous System

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A concise and colourful summary of the autonomic, somatic and sensory nervous system drugs. Proven A+ notes with diagrams, examples and helpful resources streamlined into one document to save you hours of studying!

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  • September 30, 2021
  • 23
  • 2021/2022
  • Summary
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PathologicalMed
The Nervous System
Efferent: Exits from CNS to Effectors
Afferent: Approaches CNS from sensory receptors
Divisions of the Nervous System

Central Peripheral
Nervous System Nervous System
• Brain • Cranial nerves
• Spinal chord • Spinal nerves




Autonomic NS Somatic NS Sensory
Efferent: From CNS Efferent: from CNS Afferent: to CNS

Automatic: Involuntary You control: Voluntary

Found in: Found in: Found in:
Organs & Glands Skeletal Muscle Skin, Eye, Nose Ear
Cardiac Muscle
Smooth Muscle Nicotinic Receptors
at NMJ




Sympathetic PaRasympathetic
Fight-or-flight Rest & Digest

SAD BaBa Please CAN Mum (Rest & Digest)?
• Sympathetic • Parasympathetic
• ADrenergic Neurons • Cholinerginic Neurons
• Receptors: B1,a1, B2, a2 • NeuroT: AcH
• NeuroT: E & NE • Receptors: Nicotinic, Muscarinic




Sympathetic Parasympathetic
Adrenergic a1 a2 Cholinergic
AcH

SAD BaBa Please CAN Mum Rest & Digest

nicotinic muscarinic
B1 B2

Please CAN Mum (Rest & Digest)?
SAD BaBa
• Parasympathetic NS
• Sympathetic NS
• Cholinerginic Neurons
• ADrenergic Neurons
• NeuroT: AcH
• Receptors: B1,a1, B2, a2
• Receptors: Nicotinic, Muscarinic
• NeuroT: E & NE
Presentation by F Khan 2021

, Autonomic Nervous System


Type s of Neurons AcH Nerveterminals


PresynapticNeuron PostsynapticNeuron Adrenaline&
AdrenalCortex
NorAdrenaline
AutonomicGanglion




ANS nerves

Sympathetic Parasympathetic
Adrenergic Cholinergic

adrenergic muscarinic
receptor receptor
Nicotinic Nicotinic
receptor receptor




Another View

Sympathetic Parasympathetic



Nicotinic:AcH Nicotinic:AcH
adrenergic




Cholinergic




Adrenergic:NE Muscarinic:AcH
B1,a1,B2,a2 M1,M2,M3




Presentation by F Khan 2021

,Sympathetic Nervous System: Adrenergic Response
SAD BaBa
Main B-Agonist Effects
B1: Cardiac Stimulation B2
+chronotropic (heart rate) • Relaxation of smooth muscle:
+dromotropic (conduction) • Lung, eye, uterus, bladder
+inotropic (contractility) • Gluconeogenesis
• ↓ Glandular Secretion
• Inhibits digestion




Smooth M. contraction
Vasoconstriction: ↑BP
Mydriasis: ↑pupil size




↓BP
Relax smooth muscle




↓BP
Relax smooth muscle

* Pre-Synaptic neurons in CNS
Reduces Sympathetic Rx




• Cardiac Stimulatory
+heart rate
+conduction
+ventricle contractility

Cardiac Depressant
-heart rate, conduction
-ventricle contractility
↓BP
Contraindicated in
asthmatics. Can cause
Bronchospasm!!


• Relaxation of Smooth M in
Lung, Eye, Uterus, Bladder.
• Gluconeogensis
• ↓ Glandular sx



Presentation by F Khan 2021

, Sympathetic Nervous System: Adrenergic Response




Presentation by F Khan 2021

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