33
Innate Host
Resistance
1
,33.1 Innate Resistance Overview
1. Identify the major components of the mammalian host
immune system
2. Integrate the major immune components and their
functions to explain in general terms how the immune
system protects the host
2
, Host Resistance Overview
• Most pathogens (disease causing microbes)
– must overcome surface barriers and reach
underlying
– overcome resistance by host
• nonspecific resistance
• specific immune response
3
, Host Resistance Overview…
• Immune system
– composed of widely distributed cells, tissues,
and organs
– recognizes foreign substances or microbes
and acts to neutralize or destroy them
• Immunity
– ability of host to resist a particular disease or
infection
• Immunology
– science concerned with immune responses
4