This document will provide you all information about the drugs that are used to treat the Tubercular infections in human beings . It will also provide you the brief knowledge of this drugs about their structure, modification in their structure and its effect on drugs activity, how really the drug a...
, Introduction
Tuberculosis (often called TB) is chronic bacterial infection caused by
“MYCOBACTERIUM TUBERCULOSIS, M. Bovos.
It contains unusual cell wall.
The cell wall has a high lipid content, resulting high degree of
hydrophobicity and resistance to alcohol, acids, alkalies and some
disinfefectants.
This organism usually attacks or affects almost any tissue and lungs,
but can also affect the CNS (meningitis),Circulatory system,
Genitourinary system, Bones, joints.
It is characterized by the formation of nodular bodies or
tubercles( hence the name tuberculosis) •
It is one of the most deadly and common major infectious disease
,Symptoms of TB
An unproductive cough.
Feeling tired all the time. Weight loss, loss of appetite, Night
time sweating.
Fever, Coughing up blood.
Fatigue, night sweats,constant tiredness.
Chest x-ray examination reveals changes like pleural effusion
(increase volume of pleural space), diffuse infiltrates in lung
parenchyma. Untreated cases may show systemic secondary
amyloidosis ( infiltration of liver, kidneys, spleen and other
tissues with amyloid.
TB spread person to person through the air.
, When people with TB in their lungs or throat cough,
laugh, sneeze, sing or even talk the germs that cause
TB may be spread into the air, if another person
breaths in these germs there is a chance that they will
become infected with TB.
Tuberculosis Treatment
Because administration of a single drug Often leads to
the development of a bacterial population resistant to
the drug.
Effective treatment of TB must contain multiple
drugs to which the organisms are susceptible.
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