Stuvia.com - The Marketplace to Buy and Sell your Study Material
NR565Exam Fi
nalSt
udyGui
de2021
An
tac
ids
:we
akb
ase
sth
atr
eac
twi
thh
ydr
och
lor
ica
cidt
ofor
msa
lt&wa
ter
.
Usedinthetreatme ntofHyp eraci
di
ty,GERD, PUD,hyperphosphat
emia,andc al
ci
umd ef
ici
ency
Conta
inc omb in
ationsof
metalli
cca t
ion(aluminum,c al
ciu
m, ma gnesi
um, andsodium)
andb asi
ca nion(hydroxi
de,b i
car
bon at
e ,ca
rbonate,
c i
tr
ate,andtri
si
li
cate
)
Ph
arma
codynami cs,Pharma cokine
tics,Pharma c
othe r
a p
eutic
s
Neutr
ali
zeGa s t
ri
cAc idit
y(caus e
s^p Hofthes tomacha ndduodenalbulb)
I
nhibi
tproteolyt
ica c
t i
vi
tyofp epsi
n
I
ncreaselowe resoph ageal
s phin
ctertone
Aci
d-neutra
li
z i
ngc apa c
it
yANCv ari
esb et
we enp r
oductsexpressedinmEqs
I
fingest
e dinaf asti
ngs ta
te,an t
aci
d sreduceac i
dit
yforapproxi
ma t
ely20to4 0minut
es
I
ftaken1h ra ft
erame al
,acidit
yisreducedfor2t o3h rs
Asecondd os etakena f
terame al
ma int
ainsreduceda ci
dit
yformoret ha
n4h rsaft
ertheme a
l
Theacti
onofa nt
a ci
dsoc curslocal
lyintheGI t
ractwithminimalabsorpt
ion,mini
malme t
abol
ism
AL
Lan
tac
idsa
rec
ont
rai
ndi
cat
edi
nth
epr
ese
nceofs
eve
rea
bdomi
nal
pai
nofu
nkn
ownc
aus
e,e
spe
cia
ll
yif
a
ccomp
ani
edb
yfever
-
HIGHSODI
UMcont
ent
:pt
sw/HTN,
CHF
,ma
rke
dre
nal
fai
l
ure
,oronl
ow-
sod
iumd
iet
sne
edt
ous
elows
odi
um
p
rep
ara
tion
-
Con
cur
ren
tadmi
ni
st
rat
ionwi
the
nte
ric
-coa
teddr
ugs
,de
str
oyst
hec
oat
ing
=al
te
rsa
bsor
pti
on,
^th
eri
skf
or
a
dve
rsee
ffe
cts
-
Admi
ni
s t
rat
ionsshoul
dbes e
parate
db yatl
east2hourst
odecr
eased
rug/dr
ugi
nter
acti
ons
Ca
lci
umbasedantaci
ds:TUMS,Cal
trat
e,Cal
carb
Pre
sc r
ibe
dtotrea
tcalci
umd ef
ici
entst
ates
,i.
e.ch
ron
icren
alf
ail
ure
,pos
t-menop
ause,
ando
ste
opor
osi
s
Us
edt
obi
ndp
hos
pha
tesi
nCRF
Re
qui
reVi
tami
nDf
ora
bsor
pti
onf
romt
heGI
tra
ct
E
xcr
ete
dma
inl
yinf
ece
s,2
0%i
nur
ine
ADR:Con
tra
indi
cat
edi
nth
epr
ese
nceofh
ype
rca
lce
miaa
ndr
ena
lca
lcu
liCa
n
c
aus
econ
sti
pat
ion
-in
cre
aseb
ulk
,fl
ui
dsa
nd mob
il
it
y,s
tool s
oft
ene
r
Admi
ni
st
ere
d30
min
-1h
rone
mpt
yst
oma
chor3
hra
fte
rme
als
Sh
oul
dnotb
ead
min
ist
ere
dwi
thf
oodc
ont
ain
ingl
arg
eamou
ntsofox
ali
cac
id(
spi
nac
h,r
hub
arb
),or
p
hyt
ica
cid(
bra
n,c
ere
als
),t
heyd
ecr
eas
eth
eab
sor
pti
onofc
alc
ium
Ta
kin
gw/f
ood
scon
tai
ni
ngp
hos
phor
us(
mil
k,d
air
y)c
anl
eadt
omi
l
k-a
lka
lis
ynd
rome(
N/V,
con
fus
ion
,
h
ead
ach
e).
A
lu
minu
mi sn
o t
ea s
i
lyr
emoved
Taki
ngwi
thac
idi
cfr
uitj
uic
eimproveabsor
pti
on
b
ydial
ys
isb/ci
ti
sb ou
ndto Alu
minumbase
d:Alt
erna
GE L
,Amp h
ojel
,Myl
an t
a
a
lb
umin&tra
n s
ferr
i
n=d onot
c
rossdi
al
ysi
sme mbra
ne I
nhi
bi
tsmoot
hmu scl
econt
racti
onandslowga
str
ice
mpt
yi
ng
Us
edt
obi
ndp
hos
pha
tesi
nCRF
Notabs
orbablewit
hroutin
eu se
Al
uminumc oncen
trat
edinth eCNS
Bi
ndwithphosphat
ea ndexc r
ete
dinfece
s
Pr
olon
ge duseinpat
ientswithrena
lfa
il
urema
yresu
lti
ndi
al
ysi
sos
teoma
lac
ia
Al
umi n
u mdeposi
tsinb oneandost
eomal
aci
aoccu
rs
Downloaded by: kishe | papiglitch@gmail.com
Distribution of this document is illegal
, Stuvia.com - The Marketplace to Buy and Sell your Study Material
E
lev
ate
dal
umi
numt
is
suel
eve
lsc
ont
ri
but
etot
hed
eve
lop
men
tofd
ial
ysi
sen
cep
hal
opa
thyUs
edt
otr
eat
h
ype
rph
osp
hat
emi
ainp
tsw/r
ena
lfa
il
ure&p
hos
pha
ter
ena
lst
onep
rev
ent
ionCa
nca
usec
ons
ti
pat
ion
-
i
ncr
eas
ebu
lk,
fl
ui
dsa
ndmob
il
it
y,s
tool
sof
ten
er
Downloaded by: kishe | papiglitch@gmail.com
Distribution of this document is illegal
, Stuvia.com - The Marketplace to Buy and Sell your Study Material
. Ma
3 gne
siu
mba
sed
:Mi
l
kofma
g,Ma
alox
,My
lan
ta
Ca
nbeu
sedt
otr
eatma
gne
siu
mde
fic
ien
cie
sfr
omma
lnu
tri
ti
on,
alc
ohol
i
sm,
orma
g-d
epl
et
ingd
rug
s
Th
ema
lfu
nct
ion
ing
Con
tra
ind
ica
tedi
npa
tie
ntswi
thr
ena
lfa
il
ure&u
sedwi
thc
aut
ioni
npt
swi
thr
ena
lin
suf
fi
ci
enc
y
k
idn
eyc
ann
ote
xcr
ete Notabsor
bablewit
hrout
ineuse
ma
gne
siu
m=
h
ype
rma
gne
semi
a
Exc
rete
dintheuri
ne
Contr
ain
dicat
edinpat
ien
tswit
hre
nal
fai
l
ure
,us
ewi
thc
aut
ionf
orp
ati
ent
swi
tha
nyd
egr
eeo
fre
nal
i
nsu
ffi
ci
ency
oMa l
fun
cti
oni
ngk
idn
eyi
sun
abl
etoe
xcr
etema
gne
siu
man
dhy
per
mag
nes
emi
ama
yre
sul
tCa
n
c
aus
edi
arr
hea
-in
cre
asef
ibe
rin
tak
e(Al
kal
osi
sma
yoc
curi
nre
nal
imp
air
men
t)
Cl
ini
cal
Usea
ndDo
sin
g
Downloaded by: kishe | papiglitch@gmail.com
Distribution of this document is illegal
, Stuvia.com - The Marketplace to Buy and Sell your Study Material
Ra
tio
naldr
ugs elec t
ion
ANC, sodiu mc ontent,andc ost
Comb inationp r
od uctswi tha l
u minumh y
drox id
ea ndma gnesiumh ydr
oxi
deh av
etheh i
ghestANC( us
eis
mod eratetos eve r
edi se a
s e
Moni
tor
ing
Serump hospha te,
p otassiu m,an dcalciu
md u r
ingchron i
cu se
Thesed rug sma yc ausei nc r
eas edserumc alc i
uma ndd e cr
ea seds er
ump hosphat
e
Chron i
cma gnesiumh ydrox i
deu sema yc ausee levate
dMgl e velsinpati
ent
swi t
hrenalfa
il
ureortheelder
lywit
h
decrea se
dr enal fu
n ction
Pa
tie
nteducati
o n
Takea sp rescri
b ed,esp eciall
yre l
atedtome alt
ime s
Take1 -3h rsafterme alsa n datb edt
ime
Chewa blet abl
etsc hewt h orough l
yan ddri
n kh al
fag lassofwa ter
Shakes us pensionsb eforea dmi nis
trati
on
Ma nyd r
ugi nteract
ion s,se paratedose sby2h oursapa r
t
Calci
u mb a seda nt
a cidss houldn otbea dmin ist
erwithf oodc ontaini
nglar
gea mountsofoxali
cacid(sp
inach,
r
h ubarb)orp hytica ci
d( bran s,
cereals)d ecreaseab sorpti
on
Avoidtakin gwithfoodc on tai
ningp hosphoru s(milk,dairyprodu ct
s)canc a
usemi l
k-
a l
kal
isyndr
ome( NV,
confus i
on,HA)
Cons ul
tp rovi
d er:beforeta kinga nt
acidsformor ethan2we ek sifap r
oble
mr ecur
s,i
freli
efisnotobt
ained,ori
f
symp tomsofGI bl
eed ing(b l
ack,tarr
ys tools,coff
e eg r
ou nde mesis
Aluminuma ndc alciuma n tacidsma yc ausec onsti
p at
ion :i
ncrea sebulk
,incr
easefl
uidint
ake,andmore
mob i
lity,
stool softene d
Ma gnesiuma ntaci
d sma yc aused i
arrhea,i
n creasefiber
Avoids mok i
ng,a voidf l
a tlyingb odyp ositionwh il
es lee
ping ,foodsthatir
rit
atetheg as
tri
cmu cosa( spi
cy
f
ood
s),ors
ti
mul
atea
cidp
rod
uct
ion(
alc
ohol
)an
dfood
sth
atd
ecr
eas
elowe
res
oph
age
als
phi
nct
ert
one
(
caf
fei
ne,
choc
ola
te,
fat
tyf
ood
s)
Downloaded by: kishe | papiglitch@gmail.com
Distribution of this document is illegal
