Class notes
Spermatogenesis
- Course
- Institution
University of Edinburgh Lecture notes for Reproductive Biology 3 Lecture "Spermatogenesis"
[Show more]
Seller
Follow
alexgpegg
Reviews received
Content preview
Spermatogenesis• Spermatogenesis is a process of change
o One spermatogonium becomes many spermatozoa
o Diploid spermatogonia become haloid, genetically diverse spermatozoa
▪ Meiosis forms haploid, genetically diverse sperm
o Round spermatogonia become tadpole shaped spermatozoa
o
• Spermatogenesis occurs in three phases
o 1st phase- proliferative, reason we get so many sperm
o 2nd phase- meiosis, gives us genetically diverse haploid cells
o 3rd phase- spermiogenesis, morphological change
• Spermatogenesis occurs in the seminiferous tubules
o Sperm move from the basement membrane to the lumen of the tubule
▪ Spermiogenesis occurs at the apical lumen membrane
o Their movement is helped by Sertoli cells
o
, • Phase 1- proliferation of spermatogonia
o In this stage, one spermatogonium becomes many spermatozoa
o Spermatogonia undergo mitosis to provide lots of cells for meiosis
o Spermatogonial stem cells either self-renew or commit to differentiation
▪ Different nomenclature is found in different species
▪
▪ “A” type spermatogonia are found in mice and other species
• In mice differentiated spermatogonia are still A type
o “As” cell is a single spermatogonia
o “Apr” is a paired spermatogonia
o “Aal” are 4, 8 or 16 cells that are chained together
• In humans and other primates, differentiated spermatogonia are
“B” type
o “Ad” is a true stem cell- it doesn’t divide unless cells are
damaged
• The spermatogonial stem cell niche is a specialised physical and chemical
environment
o The niche receives chemical signals from many areas such as Leydig cells,
Sertoli cells, lymphatics and others
▪ Signals work to maintain the niche
o The stem cell niche is always in contact with the basement membrane
o Spermatogonium are a type of physical signal the niche receives
o
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through EFT, credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying this summary from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller alexgpegg. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy this summary for R105,10. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
85443 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy summaries for 14 years now