100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
Pharmacology 6: Hypertension R190,26
Add to cart
Quickly navigate to
Preview
  2.  
  3. Imperial College London (ICL)
  4.  
  5. Pharmacology

Class notes

Pharmacology 6: Hypertension
 0 purchase
  • Course
  • Pharmacology
  • Institution
  • Imperial College London (ICL)

Lecture notes from Imperial College London, Medical Biosciences BSc, 2nd year, Pharmacology module. PHAR 6, hypertension: treatments that are currently prescribed for hypertension, focusing on their pharmacodynamics to understand how these different drugs lower blood pressure and considering som...

[Show more]

Preview 2 out of 9  pages

Document information

  • September 25, 2023
  • 9
  • 2022/2023
  • Class notes
  • Mahsa samadi
  • All classes

Subjects

  • hypertension
  • pharmacology
  • treatments
  • blodd pressure
  • pharmacodynamics
  • side effects
  • renin angiotensin
  • calcium channel
  • kidney
  • protein
  • efficacy
  • adherence
  • anti hypertensive

Written for

  • Imperial College London (ICL)
  • Unknown
  • Pharmacology
All documents for this subject (11)

Seller

avatar-seller
lisaribau

Content preview

Hypertension
What is hypertension ?
- condition in which blood pressure is too high
=> arterial vessels specifically: blood pushes against arterial walls
- P (pressure) = F (force) / A (area)
=> Blood Pressure = Force exerted by blood / Area of arterial wall
- blood pressure measured at brachial artery (upper arm)
=> systolic blood pressure: max pressure (heart fully contracted)
=> diastolic blood pressure: min pressure (heart fully relaxed)
=> measured in millimetres of mercury (mmHg)
- there is always force exerted on arteries (never 0)
=> elastic recoil of arteries (Windkessel effect)
=> blood continues to move around




-> recail back to
original shape



How to measure blood pressure
- sphygmomanometer/ blood pressure monitor:




- disturbs regular brachial blood flow by applying pressure to arm (inflate the cuff)
=> no blood flow

, - slowly released: sufficient pressure from heart to force blood through narrowed artery
=> turbulent blood flow: systolic pressure
=> stethoscope: rhythmic noises heard (Korotkoff sounds)
- pressure continually released until no sound
=> diastolic pressure (= no resistance)

S ⑪




Factors that influence blood pressure
- cardiac output (blood pumped by heart in a min): stroke V (blood pumped in 1 contraction)*heart rate
- total peripheral resistance/ systemic vascular resistance (SVR): diameter of vessels
- volume of circulating blood (determined by prod of RBCs and plasma)
- blood viscosity (consistency: thickness and stickiness)
- vessel walls elasticity (collagen + elastic fibres)
=> autonomic nervous system can control CO & total peripheral resistance: HR, vessel diameter...


- hypertensive: elevated systolic and/or diastolic BP
=> healthy BP depends on: - height & weight: affect metabolic demand of circulatory system
=> perfusion (blood delivery) of larger surface = increased CO & BP
=> BP increases during childhood
=> overweight + obesity = risk factor for increased BP
- age: lost of elasticity/ pathophysiological (ex: atherosclerosis)
=> BP increases as get older
arterial walls
fatty deposits
an




=> on contrary: height associated w/ low BP for old people

Blood pressure classifications

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through EFT, credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying this summary from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller lisaribau. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy this summary for R190,26. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

69052 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy summaries for 15 years now

Start selling
R190,26
  • (0)
Add to cart
Added