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NR 507 Advanced Pathophysiology MIDTERM EXAM 2024 CHAMBERLAIN UNIVERSITY EXAM 1 R250,88   Add to cart

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NR 507 Advanced Pathophysiology MIDTERM EXAM 2024 CHAMBERLAIN UNIVERSITY EXAM 1

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NR 507 Advanced Pathophysiology MIDTERM EXAM 2024 CHAMBERLAIN UNIVERSITY EXAM 1

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  • February 1, 2024
  • 34
  • 2023/2024
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NR 507 Advanced Pathophysiology MIDTERM EXAM 2024 CHAMBERLAIN UNIVERSITY EXAM 1 Hypersensitivity: Typ e 1 -Mediated IgE -inflammation due to mast cell degranultion -anaphylactic , asthma, hay fever treatment: epinephrine Hypersensitivity: Type 2 -Cytotoxic reaction: tissue specific -binds to the antigen ON THE CELL SURFACE -macrophages are primary effecto rs cells involved cause tissue damage or alter function Hypersensitivity 2 -Graves Disease (hyperthyroidism) -alters function not destroy -blood transfusions reaction - transfused erythrocytes are destroyed by agglutination or lysis -drug allergies -hemolytic anemia Hypersensitivity: type 3 -Not organ specific -antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released into the blood or bodi ly fluids, and the complex is then deposited in the tissues Hypersensitiv ity: Type 3 -rheumatoid arthritis -Systemic Lupus Erythematosus (SLE) -Raynaud's Hives (urticaria) Hypersensitivity Type 1 First responders to innate the immune system Neutrophils Allergic contact dermatitis Hypersensitivity Type IV Type 2 cytotoxic hypersensitivity mediated by: -IgG IgM -macrophages are primary effort cells - Serum Sickness type 3 hypersensitivity Hypersensitivity IV, -is more of a delayed immune response. -mediated T-cells attack tissue directly (no antibodies) Autoimmune -diseases in which the body makes antibodies directed against its own tissues - Primary immunodeficiency -Genetic; inherited -result of single gene defects -B and T cell deficiencies secondary immunodeficiency -acquired Common cause of secondary immunodeficiency Malnutrition Most patients diagnosed with SLE will have a positive ? antinuclear antibody (ANA ) SLE (lupus) -Facial rash -vasculitis - tissue inflammation Renal disease associated with autoimmunity? Glomerul onephritis Sjogren's syndrome Inflammation in salivary and lacrimal glands SLE Autoantibodies and auto -active t -cells against DNA and nucleoprotein Sjögren's syndrome immune changes: Autoantibodies and auto -reactive t -cells against apoptotic cells

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