Pharmacology Correct Ans - a science that draws on information
from multiple disciplines
Effectiveness Correct Ans - does what it is intended to do
Safe Correct Ans - safety cannot be assured
Selectivity Correct Ans - would do only what it is intended to do
Therapeutic objective Correct Ans - maximum benefit with
minimum harm
9 rights of med administration Correct Ans - right drug, dose,
patient, route, time, documentation, evaluation, education, to refuse care
Important to do before med administration Correct Ans -
assessment- vitals, mental status, side effect status, education
How do drugs act? Correct Ans - many work through receptor sites
and activate or inactivate cellular enzymes, neurohormones, and alters the
characteristics of the cell membrane
Agonist Correct Ans - activates receptor by binding with them,
mimics what is already in your body, intrinsic activity
Agonist examples Correct Ans - insulin, morphine
Agonist analogy Correct Ans - putting key into door to open door
and it opens
Antagonist Correct Ans - prevents receptor activation, inhibits the
action of the endogenous substances and drugs
Antagonist examples Correct Ans - Narcan, antihistamine
Antagonist analogy Correct Ans - key is placed in lock therefore
another key can't come and enter the same lock
, agonist-antagonists Correct Ans - drugs that act on both capacities
agonist-antagonist examples Correct Ans - talwin, nubain, stadol
non-receptor drugs Correct Ans - chemically neutralize, alter
osmolarity
chemically neutralize example Correct Ans - anti-acid; not binding
to anything, just going in and neutralizing the acid in the gut
alter osmolarity example Correct Ans - laxatives; changes
osmolarity by pulling water into the colon to help remove stool
how does administration affect drug intensity? Correct Ans -
medication errors, patient adherence
what are the sources of individual variations? Correct Ans -
pharmacokinetics, pharmacodynamics
how does individual variation affect intensity? Correct Ans - the
same med at the same dose will react differently on each person due to
other meds, comorbidities, genetics, ethnicity, etc.
pharmacokinetics Correct Ans - processes that affect a drug from
the time it enters the body until it leaves the body, ADME
ADME Correct Ans - absorption, distribution, metabolism,
excretion
absorption Correct Ans - time from entry into the body until it
reaches the blood stream
factors affecting absorption- route Correct Ans - oral (45 min), IV,
and IM faster than SQ (injections faster than oral)
factors affecting absorption- form Correct Ans - some tablets have
coating to delay absorption, liquids are absorbed faster than tablets
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