100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
Summary Glucocortico steroids explained R80,00   Add to cart
Quickly navigate to
Preview
  2.  
  3. University Of Pretoria (UP)
  4.  
  5. Pharmacology

Summary

Summary Glucocortico steroids explained
 56 views  0 purchase

I want to help you get through all the different drug classes in Pharmacology. I have found that students struggle to get through the amount of work. These summaries helped me get through my Honours Degree. I will soon graduate with my Masters of Science in Neurogenetics. You got this!

Preview 1 out of 2  pages

Document information

  • Unknown
  • June 19, 2019
  • 2
  • 2014/2015
  • Summary

Subjects

Connected book

book image

Book Title:

Author(s):

  • Edition:
  • ISBN:
  • Edition:

More summaries for

All for this textbook (26)

Written for

All documents for this subject (17)

Seller

avatar-seller
chanbain

Content preview

DRUG METABOLISM
TWO IMPORTANT EFFECTS:
1. The drug is made more HYDROPHILIC
 HASTENS the excretion by the kidneys
 Less-lipid soluble metabolite is not readily reabsorbed in
the renal tubules


2. The metabolites are usually LESS ACTIVE than the
parent drug

THE LIVER IS NB!




2 GENERAL TYPES OF REACTION:

PHASE 1 reactions PHASE 2 reactions
 BIOTRANSFORMATION of drugs  Drugs are made more
to a MORE POLAR metabolite HYDROPHILIC
 Introducing/unmasking a  CONJUGATION with
functional group (-OH, -NH2, -SH) endogenous compounds in
 Oxidation = most common
the LIVER
 Catalyzed by MIXED FUNCTION
OXIDASES (Cytochrome P450) TYPES OF CONJUGATION
 VERY LOW substrate specificity  Glucoronide

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through EFT, credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying this summary from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller chanbain. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy this summary for R80,00. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

67866 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy summaries for 14 years now

Start selling
R80,00
  • (0)
  Buy now