Class notes
MBY 161 Antimicrobial Drugs Notes
- Institution
- University Of Pretoria (UP)
This is a comprehensive and detailed note on Antimicrobial Drugs for MBY 161. Essential!! To your success in academics!!
[Show more]
Seller
Follow
Content preview
Narrow spectrum antibiotic: a limited range of microbial types that can beANTIMICROBIAL DRUGS affected
THEME 6: CHAPTER 20 Broad spectrum antibiotic: a broad range of microbial types that can be
affected
1.1 MICROBIAL DRUGS: The selective toxicity of antibacterial action lies in the liposaccharide outer
Antibacterial drugs: drugs that interfere with the growth of microbes within the layer of gram+ bacteria and the porins that from water-filled channels across
host this layer
Paul Elrich: ‘magic bullet’ Salvarsan 1.4 THE ACTION OF ANTIMICROBIAL DRUGS:
Selective toxicity: killing harmful microbes without damaging the host
Chemotherapy: the use of drugs to treat a disease
Alexander Fleming: penicillin produced by Penicillium against other gram-
positive bacteria
Antibiotic: a substance produced by a microbe that, in small amounts, inhibits
another microbe
1.3 PROBLEMS WITH CHEMOTHERAPY: WHY ITS EASIER TO FIND
DRUGS AGAINST PROKARYOTES THAN EUKARYOTES:
Eukaryotes resemble host cells and the drugs ends up causing greater damage
with greater side effects
The viruses are inside the cell, it takes over the cell and controls the controls
the machinery of the host cell to make viruses rather than cellular material
Representative sources of antibiotics:
Bactericidal: they kill bacteria directly
, Bacteriostatic: inhibits bacterial growth(pathogen can grow back)
1.3 THE SPECTRUM OF ANTIMICROBIAL ACTIVITY:
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through EFT, credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying this summary from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller anyiamgeorge19. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy this summary for R190,79. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
70840 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy summaries for 14 years now