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ONS Chemotherapy Immunotherapy Certificate Questions with Correct Answer1
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ONS Chemotherapy Immunotherapy CertificateQuestions with Correct Answers
Define neoadjuvant therapy Correct Ans ✓✓ Treatment is given prior to
surgery to shrink the tumor
Define adjuvant therapy Correct Ans ✓✓ Additional cancer treatment
given after the primary treatment to lower the risk that the cancer
reoccur
3 subcategories of alkylating agents: Correct Ans ✓✓ 1. Nitrogen
mustards
2. Platinum-based agents (do not possess an alkyl group but still termed
alkylating agents as they work similarly)
3. Nitrosoureas
Common alkylating agents: Correct Ans ✓✓ Cyclophosphamide
(Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Common platinum-based agents: Correct Ans ✓✓ Cisplatin (Platinol)
Carboplatin (Paraplatin)
,What is unique about nitrosoureas agents? Correct Ans ✓✓ Able to
cross the blood-brain barrier; can be effective in treating some brain
tumors
Common nitrosoureas agents: Correct Ans ✓✓ Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with late doses of: Correct Ans ✓✓
Carboplatin
These agents are typically categorized as highly emetogenic: Correct
Ans ✓✓ 1. Alkylating agents
2. Nitrosoureas
Pre-administration labs for alkylating agents and nitrosoureas: Correct
Ans ✓✓ BUN
Creatinine
CBC w/ diff
What is the medication Mesna used for? Correct Ans ✓✓ Bladder
protectant with administration of cyclophosphamide or ifosfamide
, Instruct pts receiving ________ to avoid exposure to cold air and
consuming cold fluids for 3-4 days following treatment Correct Ans ✓✓
Oxaliplatin
How do antimetabolites function? Correct Ans ✓✓ By blocking DNA
and RNA growth by interfering with enzymes needed for normal cell
metabolism
Antimetabolites work in the ___ phase. Correct Ans ✓✓ S
Common side effects of antimetabolites: Correct Ans ✓✓
Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Common antimetabolite drugs: Correct Ans ✓✓ Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
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